Publications by authors named "Rina Demjaha"
Background: Immune cell metabolism governs the outcome of immune responses and contributes to the development of autoimmunity by controlling lymphocyte pathogenic potential. In this study, we evaluated the metabolic profile of myelin-specific murine encephalitogenic T cells, to identify novel therapeutic targets for autoimmune neuroinflammation.
Methods: We performed metabolomics analysis on actively-proliferating encephalitogenic T cells to study their overall metabolic profile in comparison to resting T cells.
Background: Limited resources often hinder regular cognitive assessment of people with multiple sclerosis (pwMS) in standard clinical care. A self-administered iPad®-based cognitive screening-tool (Processing Speed Test; PST) might mitigate this problem.
Objective: To evaluate the PST in clinical routine.
Article Synopsis
- This study investigates serum neurofilament light chain protein (sNfL) levels in patients with essential tremor to explore its potential link to neurodegeneration, comparing it with healthy controls over time.
- Using data from a movement disorders registry, researchers found that patients with essential tremor had significantly higher sNfL levels than controls, which increased over the five-year follow-up period.
- The results suggest that early neurodegeneration may be involved in essential tremor, as greater increases in sNfL were associated with worsening tremor and cognitive issues in patients with a shorter disease duration.
Background: Besides demographics and clinical factors, psychological variables and brain-tissue changes have been associated with fatigue in persons with multiple sclerosis (pwMS). Identifying predictors of fatigue could help to improve therapeutic approaches for pwMS. Therefore, we investigated predictors of fatigue using a multifactorial approach.
View Article and Find Full Text PDFPatient Satisfaction with Health Services at the Emergency Center of the University Clinic in Prishtina.
Pril (Makedon Akad Nauk Umet Odd Med Nauki)
November 2022
: Safety is a fundamental principle in patient care as well as a key component of quality management of health services. Improving patient safety requires constant energy, including all individuals who have direct or indirect contact with the patient. This means enhancing the approach towards the patient, modifying the workplace, improving the performance of the staff and redesigning systems with the aim of reducing patient risk.
View Article and Find Full Text PDFBackground: Serum glial fibrillary acidic protein (sGFAP) has been proposed as a biomarker in various neurological diseases but has not yet been systematically investigated in patients with cerebral small vessel disease (CSVD). We explored whether sGFAP levels are increased in stroke patients with MRI-confirmed recent small subcortical infarcts (RSSI) and analyzed the subsequent course and determinants of sGFAP longitudinally.
Methods: In a prospectively-collected cohort of stroke patients with a single RSSI (n = 101, mean age: 61 years, 73% men), we analyzed brain MRI and sGFAP using a SIMOA assay at baseline and at 3- and 15-months post-stroke.