Publications by authors named "Rimma Dushkes"
Article Synopsis
- The study evaluated the impact of daily vitamin D supplementation on reducing the risk of upper respiratory infections (URI) in older adults with varying levels of vitamin D.
- It involved over 15,000 participants in a randomized trial comparing vitamin D3 (2000 IU/day) to a placebo, focusing on self-reported URI incidents over one year.
- Results showed no significant difference in URI risk overall, even among those with low initial vitamin D levels, indicating the need for further research to explore potential subgroup effects.*
A diet supplemented with vitamin D and marine omega-3 fatty acids may prevent and treat painful disorders by promoting the resolution of inflammation. However, large, randomized placebo-controlled trials evaluating the effects of supplementation with omega-3 fatty acids and vitamin D on the presence and severity of pain are lacking. VITamin D and OmegA-3 triaL-Pain (VITAL-Pain) is an ancillary study to the VITAL trial, a large randomized, double-blind, placebo-controlled trial of vitamin D (2000 IU/day) and omega-3 supplementation (1 g/day) over 5.
View Article and Find Full Text PDFImportance: Preventive strategies for frailty are needed. Whether supplements with anti-inflammatory properties, such as vitamin D3 or marine omega-3 fatty acids, are useful for frailty prevention is unknown.
Objective: To test the effects of vitamin D3 and omega-3 supplements on change in frailty in older individuals.
Importance: Results of several small randomized clinical trials have suggested that supplements of marine ω-3 fatty acids may be beneficial in treating signs and symptoms of dry eye disease (DED). However, randomized clinical trial data to examine whether ω-3 fatty acid supplements can prevent DED are lacking.
Objective: To evaluate whether long-term daily supplementation with marine ω-3 fatty acids prevents the development of DED.
Purpose: This paper describes the Women's Health Accelerometry Collaboration, a consortium of two prospective cohort studies of women age 62 years or older, harmonised to explore the association of accelerometer-assessed physical activity and sedentary behaviour with cancer incidence and mortality.
Participants: A total of 23 443 women (age mean 73.4, SD 6.
Background & Aims: The effects of vitamin D on risk of colorectal cancer precursors are not clear. We examined the influence of vitamin D supplementation on risk of colorectal adenomas and serrated polyps in a prespecified ancillary study of a large-scale prevention trial (the vitamin D and omegA-3 trial, VITAL) of individuals who were free of cancer and cardiovascular disease at enrollment.
Methods: In VITAL trial, 25,871 adults with no history of cancer or cardiovascular disease (12,786 men 50 years or older and 13,085 women 55 years or older) were randomly assigned to groups given daily dietary supplements (2000 IU vitamin D and 1 g marine n-3 fatty acid) or placebo.
Importance: Marine ω-3 fatty acid has been suggested to protect against colorectal cancer.
Objective: To assess the effect of daily marine ω-3 fatty acid supplementation on the risk of colorectal cancer precursors, including conventional adenomas and serrated polyps.
Design, Setting, And Participants: This study was a prespecified ancillary study of the placebo-controlled randomized clinical trial VITAL (Vitamin D and Omega-3 Trial).
Objective: To evaluate the association between migraine and incident cardiovascular disease and cardiovascular mortality in women.
Design: Prospective cohort study among Nurses' Health Study II participants, with follow-up from 1989 and through June 2011.
Setting: Cohort of female nurses in United States.
Background: Despite widespread use of multivitamin supplements, their effect on cognitive health-a critical issue with aging-remains inconclusive. To date, no long-term clinical trials have studied multivitamin use and cognitive decline in older persons.
Objective: To evaluate whether long-term multivitamin supplementation affects cognitive health in later life.