Publications by authors named "Rim Belkaid"
Article Synopsis
- The study investigated the effects of INV-202, a new cannabinoid type-1 receptor inverse agonist, on kidney function in a mouse model of type-1 diabetes induced by streptozotocin.
- Mice were treated with various doses of INV-202 for 28 days, showing decreased urinary urea and albumin excretion compared to untreated diabetic mice, along with improvements in the urinary albumin to creatinine ratio.
- INV-202 also reduced kidney weight and podocyte loss, restored gene expression for podocyte proteins, and decreased levels of angiotensin II, indicating potential benefits for diabetic nephropathy.
