Indications for ordering thyroid-stimulating hormone in noncritically ill adult inpatients-A Delphi consensus recommendation.

Background: Thyroid-stimulating hormone (TSH) is ordered commonly among inpatients, but the possibility of nonthyroidal illness syndrome challenges interpretation.

Objective: Our objective was to obtain Canadian consensus on appropriate indications for ordering TSH in the first 48 h following presentation of a noncritically ill internal medicine patient.

Design, Setting And Participants: Canadian endocrinologists with inpatient expertise were invited via snowball sampling to an online 3-round Delphi study.

Assessment of site-specific X-ray procedure codes for fracture ascertainment: a registry-based cohort study.

Unlabelled: Site-specific X-ray procedure codes are a useful ancillary source of information for identifying fractures in healthcare administrative and claims data.

Introduction: Real-world evaluation of fracture epidemiology at the population level from electronic healthcare information, such as administrative data, requires comprehensive data sources and validated case definitions. Only hip fractures are routinely hospitalized, and the identification of most osteoporosis-related fractures which are non-hospitalized fractures remains challenging.

Exercise training prevents the development of cardiac dysfunction in the low-dose streptozotocin diabetic rats fed a high-fat diet.

This study tested the hypothesis that exercise training would prevent the development of diabetes-induced cardiac dysfunction and altered expression of sarcoplasmic reticulum Ca(2 +)-transport proteins in the low-dose streptozotocin-induced diabetic rats fed a high-fat diet (HFD+STZ). Male Sprague-Dawley rats (4 weeks old; 125-150 g) were made diabetic using a high-fat diet (40% fat, w/w) and a low-dose of streptozotocin (35 mg·(kg body mass)(-1)) by intravenous injection. Diabetic animals were divided among a sedentary group (Sed+HFD+STZ) or an exercise-trained group (Ex+HFD+STZ) that accumulated 3554 ± 338 m·day(-1) of voluntary wheel running (mean ± SE).