Effect of calcium vs. placebo on long-term outcomes in patients with out-of-hospital cardiac arrest.

Objective: The Calcium for Out-of-hospital Cardiac Arrest (COCA) trial was a randomized, placebo-controlled, double-blind trial of calcium for out-of-hospital cardiac arrest. The primary and secondary outcomes have been reported previously. This article describes the long-term outcomes of the trial.

Effect of Intravenous or Intraosseous Calcium vs Saline on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.

Importance: It is unclear whether administration of calcium has a beneficial effect in patients with cardiac arrest.

Objective: To determine whether administration of calcium during out-of-hospital cardiac arrest improves return of spontaneous circulation in adults.

Design, Setting, And Participants: This double-blind, placebo-controlled randomized clinical trial included 397 adult patients with out-of-hospital cardiac arrest and was conducted in the Central Denmark Region between January 20, 2020, and April 15, 2021.

A Case of an Advanced Chain of Survival in Penetrating Cardiac Injury.

The survival rate of penetrating cardiac trauma is dismal, with only a few patients reaching the hospital with any signs of life. Short transport time and close proximity to the trauma center are positive factors for survival. We report the successful case of a 21-year-old male with penetrating cardiac injury and tension-pneumothorax with long distance to a trauma facility.

Prehospital triage of patients suffering severe dyspnoea using N-terminal pro-brain natriuretic peptide, the PreBNP trial: a randomised controlled clinical trial.

Purpose: The purpose of this study was to examine whether the addition of brain natriuretic peptide measurement to the routine diagnostic work-up by prehospital critical care team physicians improves triage in patients with severe dyspnoea.

Methods: Prehospital critical care team physicians randomly assigned patients older than 18 years with severe dyspnoea to routine diagnostic work-up or diagnostic work-up with incorporated point-of-care N-terminal pro-brain natriuretic peptide (NT-proBNP) measurement. The primary endpoint was the proportion of patients with dyspnoea of primary cardiac origin triaged directly to a department of cardiology.

[Fatal intoxication with the new designer drug 25C-NBOMe].

This is a case report of a 22-year-old man, who snorted the content of three capsules of the new designer drug 25C-NBOMe (2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine). 1-2 hours after the intake he became unconscious with generalized seizures, so he was intubated prehospitally and brought to the local hospital. At admission he had acute renal failure and was severely metabolic acidotic with potassium 8.

[Fentanyl tea].

Fentanyl is a potent synthetic opioid. Abuse of fentanyl patches is rarely occurring, but has been described. In this case a patient had been drinking hot tea mixed with two fentanyl patches.

Lower versus higher hemoglobin threshold for transfusion in septic shock.

Background: Blood transfusions are frequently given to patients with septic shock. However, the benefits and harms of different hemoglobin thresholds for transfusion have not been established.

Methods: In this multicenter, parallel-group trial, we randomly assigned patients in the intensive care unit (ICU) who had septic shock and a hemoglobin concentration of 9 g per deciliter or less to receive 1 unit of leukoreduced red cells when the hemoglobin level was 7 g per deciliter or less (lower threshold) or when the level was 9 g per deciliter or less (higher threshold) during the ICU stay.

[Fatal pulmonary embolism after acute bilateral minor surgery].

Venous thromboembolism (VTE) is a quite common and well-documented complication after major surgery. The causes are multifactorial, but prophylactic antithrombotic treatment reduces the risk of VTE. In Denmark, all hospitals have prophylactic antithrombotic regimes for major surgery.

[Pneumomediastinum induced by sniffed cocaine].

The increasing availability and use of cocaine stresses the importance that physicians are aware of the medical complications of the abuse. This case report describes a 24 year-old man who got chest pain after the snorting of 6 g of cocaine. A chest X-ray revealed a pneumomediastinum, which was confirmed by a computed tomography of the thorax.

[Chronic obstructive pulmonary disease as frequent secondary diagnosis at medical department].

Introduction: Patients with Chronic Obstructive Pulmonary Disease (COPD) often suffer from comorbidities. This study evaluates the need for hospitalization due to comorbidity in COPD patients and the diagnoses these patients have, and it investigates whether COPD comorbidity prolongs the hospital stay.

Material And Methods: A cross-sectional study performed at a department of internal medicine.