Publications by authors named "Rikke Kamp Damgaard"
Article Synopsis
- Active surveillance for cervical intraepithelial neoplasia grade 2 (CIN2) has been increasingly used in Denmark, focusing on women of reproductive age, and aims to evaluate clinical and socioeconomic factors influencing management methods.
- A nationwide study analyzed data from 27,536 women diagnosed with CIN2 between 1998 and 2020, revealing that younger, HPV-vaccinated women were more likely to undergo active surveillance compared to those who had a large loop excision (LLETZ).
- The trend showed a significant rise in active surveillance from 21.7% in 2004 to 73.6% in 2019, although the proportion of younger women opting for this method decreased over time.
Article Synopsis
- Active surveillance is increasingly being used instead of excisional treatment for younger women with cervical intraepithelial neoplasia grade 2 due to high regression rates and lower risk of preterm birth associated with surveillance.* -
- The study examined HPV type-specific persistence/progression in 455 women aged 23 to 40 who were diagnosed with cervical intraepithelial neoplasia grade 2 at Aarhus University Hospital between 2000 and 2010, highlighting the need for early identification of women at risk.* -
- Results indicated that over half (52.2%) of the participants exhibited persistent or progressive disease, emphasizing the importance of monitoring HPV types to assess risk during active surveillance.*
Article Synopsis
- The study assessed the long-term risk of cervical cancer in women aged 18-40 with untreated cervical intraepithelial neoplasia grade 2 (CIN2) compared to those who received immediate treatment (LLETZ).
- It involved 27,524 women diagnosed from 1998 to 2020, finding that 104 developed cervical cancer during follow-up, with a higher incidence in the active surveillance group.
- Results indicated that while the cervical cancer risk was similar between both groups initially, it significantly increased for the active surveillance group after two years, highlighting the need for close monitoring in these patients.
Introduction: Many countries have adopted active surveillance in women with cervical intraepithelial neoplasia grade 2 (CIN2), leaving the lesion untreated. However, there is a lack of consensus on the eligibility criteria for active surveillance across countries, with some abstaining from active surveillance in women with human papilloma virus 16 (HPV16) or a high-grade cytology. Here, we aimed to describe the distribution of HPV genotypes, age, and cytology in women undergoing active surveillance for CIN2.
View Article and Find Full Text PDFIntroduction: Cervical intraepithelial neoplasia grade 2 (CIN2) represents a spectrum of lesions with variable progression and regression. Pathological diagnosis of CIN2 is subjective and poorly reproducible. Accurate diagnosis and identification of different patterns of CIN2 related to outcome are essential to reduce the risks of overtreatment or undertreatment.
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