Publications by authors named "Rikiya Takashina"
Background And Purpose: Radiation-induced lymphopenia (RIL) may be associated with a worse prognosis in pancreatic cancer. This study aimed to develop a normal tissue complication probability (NTCP) model to predict severe RIL in patients with pancreatic cancer undergoing concurrent chemoradiotherapy (CCRT).
Materials And Methods: We reviewed pancreatic cancer patients treated at our facility for model training and internal validation.
Article Synopsis
- The study aimed to validate the Graded Prognostic Assessment for lung cancer (Lung-molGPA) in Japanese non-small cell lung cancer (NSCLC) patients with brain metastasis (BM) by analyzing factors affecting survival.
- A retrospective analysis of 294 NSCLC patients treated with radiotherapy revealed median overall survival (OS) times significantly varied based on GPA scores and treatment history, particularly noting the benefits of osimertinib in adenocarcinoma patients with gene mutations.
- Although survival varied across PD-L1 expression levels, the differences were not statistically significant, indicating that other factors might play a more critical role in survival outcomes for patients with BM.
Hydrogels of poly(2-hydroxyethyl methacrylate) (PHEMA) with well-defined polyelectrolyte brushes of poly(sodium 4-styrenesulfonate) (PNaSS) of various molecular weights were synthesized, keeping the distance between the polymer brushes constant at ca. 20 nm. The effect of polyelectrolyte brush length on the sliding friction against a glass plate, an electrorepulsive solid substrate, was investigated in water in a velocity range of 7.
View Article and Find Full Text PDF