Characterization of the quinol-dependent nitric oxide reductase from the pathogen Neisseria meningitidis, an electrogenic enzyme.

Bacterial nitric oxide reductases (NORs) catalyse the reduction of NO to NO and HO. NORs are found either in denitrification chains, or in pathogens where their primary role is detoxification of NO produced by the immune defense of the host. Although NORs belong to the heme-copper oxidase superfamily, comprising proton-pumping O-reducing enzymes, the best studied NORs, cNORs (cytochrome c-dependent), are non-electrogenic.