No Influence of Previous Infection on ICU Admission and Mortality in Emergency Department Patients Infected with SARS-CoV-2.

Background: the geographical similarities of the Dutch 2007-2010 Q fever outbreak and the start of the 2020 coronavirus disease 19 (COVID-19) outbreak in the Netherlands raised questions and provided a unique opportunity to study an association between infection and the outcome following SARS-CoV-2 infection.

Methods: We performed a retrospective cohort study in two Dutch hospitals. We assessed evidence of previous infection in COVID-19 patients diagnosed at the ED during the first COVID-19 wave and compared a combined outcome of in-hospital mortality and intensive care unit (ICU) admission using adjusted odds ratios (OR).