Optical mammography combined with fluorescence imaging: lesion detection using scatterplots.

Using scatterplots of 2 or 3 parameters, diffuse optical tomography and fluorescence imaging are combined to improve detectability of breast lesions. Small or low contrast phantom-lesions that were missed in the optical and fluorescence images were detected in the scatterplots. In patient measurements, all tumors were visible and easily differentiated from artifacts and areolas in the scatterplots.

Diffuse optical tomography of the breast: preliminary findings of a new prototype and comparison with magnetic resonance imaging.

This paper presents an evaluation of a prototype diffuse optical tomography (DOT) system. Seventeen women with 18 breast lesions (10 invasive carcinomas, 2 fibroadenomas, and 6 benign cysts; diameters 13-54 mm) were evaluated with DOT and magnetic resonance imaging (MRI). A substantial fraction of the original 36 recruited patients could not be examined using this prototype due to technical problems.

Efficient coupling into and out of high-Q resonators.

The temporal-coupled-mode theory is directly applied to the design of devices that feature a resonator with a high quality factor. For the temporal-coupled-mode theory we calculate the decay rate of the resonator to determine the transmission properties of the device. The analysis using the decay rates requires little computational effort, and therefore the optimum device properties can be determined quickly.