Publications by authors named "Rijian Guan"

Article Synopsis
  • This research aimed to explore how systemic inflammation is related to the risk of developing prostate cancer (PCa), using data from the National Health and Nutrition Examination Survey (NHANES) and Mendelian randomization analysis.
  • The study analyzed data from 7,706 participants aged 40 and older, finding that higher levels of systemic inflammation, measured by the systemic immune-inflammation index (SII), were linked to an increased risk of PCa, with specific immune cells also showing a causal relationship with the disease.
  • The findings underscore the importance of systemic inflammation and immune responses as potentially modifiable factors that could influence the risk of prostate cancer.
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Obstructive azoospermia is a kind of common clinical disease, which often happens in epididymis, vas deferens and ejaculatory duct obstruction and accounts for male infertility. Azoospermia, which is caused by obstruction of the ejaculatory duct, is relatively rare. but the development of endoscopic technology now allows the disease to be resolved by surgery.

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Varicocele is a common abnormality, but the conventional microsurgical subinguinal varicocelectomy (CMSV) has some disadvantages. We invented Modified Inguinal Microscope-Assisted Varicocelectomy (MIMV) under local anesthesia. This study aims to evaluate MIMV by comparing it to CMSV in operating duration, time to return to normal activity, postoperative complications, achievement of natural pregnancy and improvement of semen quality for patients with infertility, pain score for those with scrotal pain, and so on.

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The effects of vitamin K2 on apoptosis in a variety of cancer cells have been well established in previous studies. However, the apoptotic effect of vitamin K2 on bladder cancer cells has not been evaluated. The aim of this study is to examine the apoptotic activity of Vitamin K2 in bladder cancer cells and investigate the underlying mechanism.

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