Dose patterns among patients using low-dose buprenorphine patches.

Objective: The objective of this study was to investigate the dose pattern of low-dose buprenorphine patches among patients in Swedish clinical practice. The clinical experts among the coauthors interpreted the results in relation to possible indications of development of tolerance and/or dependence/addiction.

Design And Setting: This was a nationwide, observational study using data from the Swedish Prescribed Drug Register.

Double-blind comparison of sertraline and placebo in stroke patients with minor depression and less severe major depression.

Background: Poststroke depression is a frequent condition and important to treat. The aim of this trial was to study the efficacy and tolerability of sertraline.

Method: In 4 Swedish stroke centers, 123 patients (aged 70.