Association of early discharge with increased likelihood of hospital readmission in first four weeks for vaginally delivered neonates.

Aim: The main aim was to determine whether hospital readmission rates by 28 days of age are elevated with early discharge (ED) in Finland. We sought to identify the causes and predictors of ED, readmission rates, admissions to the intensive care unit (ICU) and death.

Methods: The data of 333,321 infants were retrieved from nationwide registers.

Calcium supplementation during pregnancy and long-term offspring outcome: a systematic literature review and meta-analysis.

The World Health Organization currently recommends calcium supplementation for pregnant women, especially those with low calcium intakes, to reduce the risk of hypertension and preeclampsia. We aimed to evaluate the effect of this intervention on selected offspring outcomes. A systematic search was conducted in 11 databases for published randomized controlled trials (RCTs) on the effect of maternal calcium supplementation with or without vitamin D during pregnancy on selected offspring cardiovascular, growth, and metabolic and neurodevelopmental outcomes.

Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis.

Insufficient calcium intake during pregnancy may lead to maternal bone resorption and lower bone density of offspring. We evaluated the impact of supplementary calcium with or without vitamin D during pregnancy on maternal and offspring bone mineral density (BMD) and teeth firmness of the offspring. Randomized controlled trials (RCTs) were searched systematically in 11 databases.

Is birth out-of-hospital associated with mortality and morbidity by seven years of age?

Background And Aims: Compared to in-hospital births, the long-term outcome of children born out-of-hospital, planned or unplanned, is poorly studied. This study aimed to examine mortality and morbidity by seven years of age in children born out-of-hospital compared to those born in-hospital.

Methods: This study was registered retrospectively and included 790 136 children born in Finland between 1996 and 2013.

Unplanned out-of-hospital deliveries in Finland: A national register study on incidence, characteristics and maternal and infant outcomes.

Introduction: Unplanned out-of-hospital deliveries (UOHDs) have earlier been related to higher perinatal mortality and morbidity, but recent research has not paid much attention to them. Our aim was to evaluate the incidence, characteristics, risk factors, and maternal and perinatal mortality and morbidity in UOHDs in Finland.

Material And Methods: We conducted a national register study on births, causes of death and congenital anomalies for all live and stillbirths during 1996-2013.

Hospital admissions for lower respiratory tract infections after early-, late-, and post-term birth.

Background: Recent data suggest that early-term births are associated with later respiratory morbidity (LRTI), and post-term births may decrease this risk.

Objectives: The objective was to determine the impact of early-term, late-term, and post-term birth on hospital admission for LRTI up to the age of seven years. Additionally, we explored maternal and perinatal factors associated with the risk of admission for LRTIs.

Planned home deliveries in Finland, 1996-2013.

Objective: To evaluate trends and perinatal outcomes of planned home deliveries in Finland.

Study Design: All infants born in 1996-2013, excluding those born preterm, by operative delivery, and without information on birth mode or gestational age, were studied. The study group included 170 infants born at home as planned, 720,047 infants born at hospital were controls.

Visual and Hearing Impairments After Preterm Birth.

Objectives: Our aim was to determine and compare the incidences of sensory impairments among very preterm (VP) (<32 + 0/7 weeks), moderately preterm (MP) (32 + 0/7-33 + 6/7 weeks), late preterm (LP) (34 + 0/7-36 + 6/7 weeks), and term infants (≥37 weeks) and to establish risk factors of neurosensory disabilities.

Methods: This national register study included all live-born infants in Finland between 1991 and 2008. Infants who died before the age of 1 year, who had any major congenital anomaly, or had missing data were excluded ( = 21 007; 2.

Asthma and atopic dermatitis after early-, late-, and post-term birth.

Objective: To assess the incidence and risk factors of asthma and atopic dermatitis by seven years of age after early-term (ET) (37 -38 weeks), full-term (FT) (39 -40 weeks), late-term (LT) (41 -41 weeks), and especially post-term (PT) (≥42 weeks) birth.

Methods: Altogether, 965 203 infants born between 1991 and 2008 in Finland were investigated in ET, FT, LT, and PT groups. Data on asthma medication reimbursement and hospital visits for atopic dermatitis were retrieved from national health databases.

Hospital admissions for lower respiratory tract infections in children born moderately/late preterm.

Objective: To evaluate the frequency and predictors of hospital admissions for lower respiratory tract infections (LRTIs) in moderately preterm (MP, 32 to 33 weeks) and late preterm (LP, 34 to 36 weeks) infants compared to term (T ≥37 weeks) and very preterm (VP, <32 weeks) infants.

Study Design: This national register-based study covered all infants born in Finland in 1991-2008. Data on 1 018 256 infants were analyzed in four gestational age-based groups: VP (n = 6329), MP (n = 6796), LP (n = 39 928), and T (n = 965 203) groups.

The incidence and risk factors of epilepsy in children born preterm: A nationwide register study.

Objectives: The aim was to compare the incidence of epilepsy between very preterm (VP) (<32 weeks), moderately preterm (MP) (32-33 weeks), late preterm (LP) (34-36 weeks) and term infants (≥37 weeks) and to establish and compare risk factors of epilepsy in these groups.

Methods: The national register study included all live born infants in Finland in 1991-2008. Excluding infants with missing gestational age, a total of 1,033,349 infants were included in the analysis and they were analyzed in four subgroups (VP, MP, LP and term) and three time periods (1991-1995, 1996-2001 and 2002-2008).

Asthma and atopic dermatitis in children born moderately and late preterm.

Unlabelled: This national register study aimed to evaluate the need of asthma medication reimbursement and hospitalization due to asthma and atopic dermatitis up to 7 years of age in moderately preterm (MP) (32-33 weeks) and late preterm (LP) (34-36 weeks) children compared to very preterm (VP) (<32 weeks) and term (≥37 weeks) children. Altogether, 1,018,302 children born in Finland between 1991 and 2008 were assessed. The MP and LP groups received asthma medication reimbursement more frequently than term controls (8.

Out-of-hospital deliveries have risen involving greater neonatal morbidity: Risk factors in out-of-hospital deliveries in one University Hospital region in Finland.

Aim: Most Finnish births take place in hospital, but out-of-hospital deliveries (OHDs) have increased. This study evaluated trends and reasons for OHDs in the Tampere University Hospital catchment area.

Methods: The study cohort included all planned and unplanned OHDs in the Hospital area from 1996 to 2011; the control group comprised two hospital births for each OHD.

Cerebral palsy among children born moderately and late preterm.

Objective: To compare the incidence of and risk factors for cerebral palsy (CP) in moderately preterm (MP) (32(+0)-33(+6) weeks) and late preterm (LP) (34(+0)-36(+6) weeks) infants with those in very preterm (VP) (<32(+0) weeks) and term infants (≥37 weeks).

Methods: The national register study included all live-born infants in Finland from 1991 to 2008. Infants who died before the age of 1 year, had any major congenital anomaly, or had missing data were excluded.

Decreased free water clearance is associated with worse respiratory outcomes in premature infants.

Objective: The goal was to elucidate predictors of decreased free water clearance (DFWC) in very low birth weight (VLBW) infants. We hypothesized that DFWC and fluid retention are linked to the severity of pulmonary problems and prolonged respiratory support, especially to nCPAP treatment.

Methods: The investigation was carried out at Tampere University Hospital between 2001 and 2006.

[Evidence-based methods of medicine in specialization training: a neonatologic problem as an example].

One of the objectives of the qualification of medical specialists is familiarization to the scientific literature of the future special field. We describe a training project, in which doctors specializing in pediatrics collected and evaluated the current scientific data on the closure of the arterial duct in premature infants. Main emphasis in the article is put on the setting of the questions to be elucidated, acquisition of the required information, evaluation of the degree of evidence, and how reliably these questions can be answered on the basis of the current information.

Predictors of delayed first voiding in newborn.

Aim: Delay>24 h of age in neonates' first voiding attracts attention, although the phenomenon is usually benign. Earlier studies indicate that stress increases the infant's arginine vasopressin (AVP) and aldosterone secretion during birth. Our aim was to seek predictors of delayed first voiding and indirect evidence of AVP effect behind this phenomenon.

Predictors of AVP and TSH levels and the timing of first voiding in the newborn.

To evaluate obstetric predictors of umbilical cord plasma AVP levels, serum TSH levels and the timing of first voiding, 87 singleton term newborns were divided into three groups: group A, vaginal delivery (n = 30); group B, cesarean section (CS) during labor (n = 26); and group C, elective CS (n = 31). The AVP concentration was 120 (0.7-2170) ng/L in group A, 1.

Tubular proteinuria in pre-term and full-term infants.

Predictors of tubular proteinuria (alpha 1-M/crea ratio >10 mg/mmol) were sought in 100 infants of 24-32 weeks' (group 1) and 69 of 34-42 weeks' gestation (group 2). Random spot urine samples were obtained in the former group at the ages of 0-3 days, at 1-2 weeks and thereafter at 2-week intervals until the disappearance of tubular proteinuria, and in the latter one sample at a mean (SD) of 3.0 days' (1.