Bilateral hippocampal infarction as etiology of sudden and prolonged memory loss.

Sudden memory loss, with prolonged cognitive deterioration, clinically initially resembling a transitory global amnesia (TGA)-like episode, might be caused by ischemic stroke in the hippocampal regions. We report a patient with TGA-type sudden anterograde amnesia and normal head CT. Examinations revealed that the patient had several vascular risk factors and 3 tesla (T) head MRI showed ischemic lesions in diffusion-weighted images (DWI) in both hippocampi.

Fast measurement of auditory event-related potential profiles in 2-3-year-olds.

Auditory discrimination, memory, and attention-related functions were investigated in healthy 2-3-year-olds by recording event-related potentials (ERPs) to changes in five auditory features and two types of novel sounds using the fast multifeature paradigm (MFP). ERP profiles consisting of the mismatch negativity (MMN), P3a, and prominent late discriminative negativities (LDN) were obtained, for the first time, from this age group in a considerably shorter time compared to the traditional paradigms. Statistically significant responses from individual children were obtained mainly for the novel sounds.