Purpose: To study the relationship between primary open-angle glaucoma (POAG) in a cohort of patients of African descent (AD) and serum vitamin D levels.
Methods: A subset of the AD and glaucoma evaluation study III (ADAGES III) cohort, consisting of 357 patients with a diagnosis of POAG and 178 normal controls of self-reported AD, were included in this analysis. Demographic information, family history, and blood samples were collected from all the participants.
Purpose: To describe the study protocol and baseline characteristics of the African Descent and Glaucoma Evaluation Study (ADAGES) III.
Design: Cross-sectional, case-control study.
Participants: Three thousand two hundred sixty-six glaucoma patients and control participants without glaucoma of African or European descent were recruited from 5 study centers in different regions of the United States.
Objectives: To investigate the 24 h effects of bimatoprost 0.01% monotherapy on intraocular pressure (IOP) and ocular perfusion pressure (OPP).
Design: Prospective, open-label experimental study.
Purpose: To investigate the effect of brimonidine monotherapy on intraocular pressure (IOP) during the nocturnal/sleep period.
Design: Prospective, open-label experimental study.
Participants: Fifteen patients with newly diagnosed open-angle glaucoma or ocular hypertension (ages, 46-72 years).
Purpose: To compare the diurnal and nocturnal effects of brinzolamide and timolol on intraocular pressure (IOP) in patients already receiving monotherapy with latanoprost.
Design: Prospective, open-label, and crossover clinical trial.
Participants: Twenty-six patients with glaucoma or ocular hypertension (ages, 44-79 years) who were receiving treatment with 0.