Automation in radiotherapy treatment planning: Examples of use in clinical practice and future trends for a complete automated workflow.

Modern radiotherapy treatment planning is a complex and time-consuming process that requires the skills of experienced users to obtain quality plans. Since the early 2000s, the automation of this planning process has become an important research topic in radiotherapy. Today, the first commercial automated treatment planning solutions are available and implemented in a growing number of clinical radiotherapy departments.

Daily multidisciplinary COVID-19 meeting: Experiences from a French university hospital.

Objectives: In March 2020, the World Health Organization declared the coronavirus disease 2019 (COVID-19) a pandemic. In absence of official recommendations, implementing daily multidisciplinary team (MDT) COVID-19 meetings was urgently needed. Our aim was to describe our initial institutional standard operating procedures for implementing these meetings, and their impact on daily practice.

Efficacy and safety of rituximab in patients with chronic hypersensitivity pneumonitis (cHP): A retrospective, multicentric, observational study.

Background: There are chronic forms of hypersensitivity pneumonitis (cHP) that can progress to pulmonary fibrosis. There is no recommended treatment for patients whose respiratory condition continues to deteriorate in spite of antigen avoidance. Whether rituximab may be beneficial to patients with cHP is unknown.

Dual-color deep-tissue three-photon microscopy with a multiband infrared laser.

Multiphoton microscopy combined with genetically encoded fluorescent indicators is a central tool in biology. Three-photon (3P) microscopy with excitation in the short-wavelength infrared (SWIR) water transparency bands at 1.3 and 1.

[Etiological diagnosis of pulmonary hypertension: A cause of difficult diagnosis].

Introduction: Schistosomiasis associated pulmonary arterial hypertension belongs to group 1 of the pulmonary hypertension classification and should be considered in any patient with pulmonary hypertension returning from an endemic area.

Case Report: A 17-year-old patient was hospitalized for pulmonary hypertension detected during the initial assessment of viral hepatitis B-related cirrhosis with portal hypertension. The initial assessment established the diagnosis of pulmonary hypertension secondary to viral hepatitis B-cirrhosis.

Supercontinuum-seeded few-cycle mid-infrared OPCPA system.

We propose and demonstrate an OPCPA architecture emitting few-cycle pulses at 3070 nm and 1550 nm based on a high-energy femtosecond ytterbium-doped fiber amplifier pump. The short pump pulse duration allows direct seeding by a supercontinuum in the 1.4 - 1.

Spectral division amplification of a 40 nm bandwidth in a multicore Yb doped fiber and femtosecond pulse synthesis with in-fiber delay line.

A compact multicore ytterbium doped fiber amplifier has been implemented according to the spectral division scheme. It was shown that it allows amplification of pulses with about 40 nm wide spectrum. Compensation of the different spectral bands delay through bending and twist of the multicore ribbon fiber followed by appropriate setting of their phase permitted the synthesis of pulses close to 100 fs duration.

Dual-wavelength synchronous ultrashort pulses from a mode-locked Yb-doped multicore fiber laser with spatially dispersed gain.

A laser based on a ribbon multicore ytterbium doped fiber where different cores amplified different spectral bands, has been mode-locked with a single saturable absorber mirror. Tunable dual wavelength synchronized picosecond pulses were obtained. Compensation of differential cavity roundtrip times was achieved in the fiber.

Coherent beam combining with an ultrafast multicore Yb-doped fiber amplifier.

Active coherent beam combination using a 7-non-coupled core, polarization maintaining, air-clad, Yb-doped fiber is demonstrated as a monolithic and compact power-scaling concept for ultrafast fiber lasers. A microlens array matched to the multicore fiber and an active phase controller composed of a spatial light modulator applying a stochastic parallel gradient descent algorithm are utilized to perform coherent combining in the tiled aperture geometry. The mitigation of nonlinear effects at a pulse energy of 8.

Spatially dispersive amplification in a 12-core fiber and femtosecond pulse synthesis by coherent spectral combining.

A compact scheme is demonstrated for amplification and synthesis of ultrashort pulses by fiber amplifiers. Femtosecond pulses are split in 12 different spectral bands which are amplified separately in the 12 cores of a multicore ytterbium doped fiber. Combining the amplifier outputs together with the intensity and phase management of the spectral bands lead to short pulse synthesis with adjustable pulse shape.

Spatially dispersive scheme for transmission and synthesis of femtosecond pulses through a multicore fiber.

A new scheme is presented for fiber transmission of ultrashort laser pulses. A dispersive device divides the input pulses into spatially separated spectral components which are individually launched in the different channels of a multicore fiber before being recombined at the output by a second dispersive device. The parallel transmission of narrow spectral bands avoids self-phase modulation and could be appropriate to deliver high peak power pulses.

Workplace bullying and psychotropic drug use: the mediating role of physical and mental health status.

Objectives: The association between workplace bullying and psychotropic drug use is not well established. This study was aimed at exploring the association between workplace bullying, and its characteristics, and psychotropic drug use and studying the mediating role of physical and mental health.

Methods: The study population consisted of a random sample of 3132 men and 4562 women of the working population in the south-east of France.

Workplace bullying and sleep disturbances: findings from a large scale cross-sectional survey in the French working population.

Study Objectives: The purpose of this study was to explore the associations between workplace bullying, the characteristics of workplace bullying, and sleep disturbances in a large sample of employees of the French working population.

Design: Workplace bullying, evaluated using the validated instrument developed by Leymann, and sleep disturbances, as well as covariates, were measured using a self-administered questionnaire. Covariates included age, marital status, presence of children, education, occupation, working hours, night work, physical and chemical exposures at work, self-reported health, and depressive symptoms.

Double pigtail ureteral stent in pediatric urology.

We used a double pigtail ureteral stent in 16 children (aged 15 days to 13 years). Indications included: pyeloplasty (12 cases with 2 anastomotic leakages and 1 acute post-operative renal retention), renal trauma (1 case), difficult ureterocystoneostomy (1 case), urinary ascites (1 case), and abdominal tumor compression (1 case). This drainage procedure provides a useful alternative to an external tube diversion (standard ureteral stent or nephrostomy).

[Internal urinary drainage by double J stent in pediatric urology].

We used double pigtail ureteral stent in 16 children (aged 15 days to 13 years old). Indications included: pyeloplasty (12 cases with 2 anastomotic leakages and 1 acute postoperative renal retention), renal trauma (1 case), difficult ureterocystoneostomy (1 case), urinary ascites (1 case), and abdominal tumor compression (1 case). This drainage procedure provides a useful alternative to an external tube diversion (standard ureteral stent or nephrostomy).

[A rare psychogenic anejaculation. Report of a case of prolactin adenoma].

The authors report a case of prolactinoma discovered during assessment of a case of ejaculation failure attributed for more than eight years to a psychogenic cause. Because of the size of the tumour, surgical resection of the lesion left a persistent hyperprolactinaemia, which only returned to normal after treatment with bromocriptine. The persistence of sexual disorders justified adjuvant treatment with exogenous testosterone.

[Posterior epispadias with unknown complete duplicated urethra].

The authors report a case of posterior epispadias associated with complete ventral urethra only discovered during the urethroplasty phase of the operation. This malformation is a rare form of urethral duplication and should be considered in any case of apparently isolated posterior epispadias.

[Isolated urethral injury following coital faux pas. Report of a case with no associated injury of the corpora cavernosa].

An urethral lesion due to coital faux pas is usually associated with a lesion of the corpora cavernosa, but may occasionally be isolated. Suspected clinically due to the presence of urethral bleeding, the diagnosis of ruptured urethra is based on urethrography and, more importantly, urethroscopy, which appears to be more reliable for defining the complete or partial nature and the site of the rupture. Even in incomplete forms, surgical suture of the lesion appears to give better results than urinary diversion alone.

Renal oncocytoma in a child.

Oncocytoma is an exceptionally rare renal tumor in children. We report on one case of a twelve-year-old girl treated by nephrectomy.

[Carpal tunnel syndrome in children. Apropos of 4 personal cases].

Four cases of Carpal Tunnel syndrome during childhood are reported. Two of them are post traumatic cases; for one child, the syndrome was caused by hypertrophic cal six months after trauma. The other child has been operated because of a median and ulnar nerve deficit syndrome, which appeared one month after fracture.

[Hellp syndrome may precede the appearance of arterial hypertension in pregnancy toxemia].

The "Hellp syndrome" describes the association of three biological abnormalities (hemolysis, liver abnormalities and thrombocytopenia) establishing the severity of arterial hypertension during pregnancy and requiring the interruption of pregnancy as much for the child as for the mother. This article reports a case of "Hellp syndrome" which was special in that the biological abnormalities preceded the occurrence of pre-eclampsia. The signs, diagnosis, prognosis and treatment of the "Hellp syndrome" are studied in this article.