Publications by authors named "Rifat Rayhan"
Article Synopsis
- Acetylcholinesterase (AChE) is crucial in Alzheimer's disease, as inhibiting it could raise acetylcholine levels, potentially improving cognitive function.
- A study screened 2500 compounds from traditional medicinal plants, identifying 80 with good properties and narrowing down to three top candidates based on their binding affinity to AChE.
- The selected compounds underwent various evaluations, including molecular dynamics simulations and Density Functional Theory analysis, confirming their stability and potential as effective treatments for Alzheimer's disease.
Dengue fever (DF) is an endemic disease that has become a public health concern around the globe. The NS3 protease-helicase enzyme is an important target for the development of antiviral drugs against DENV (dengue virus) due to its impact on viral replication. Inhibition of the activity of the NS3 protease-helicase enzyme complex significantly inhibits the infection associated with DENV.
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