Publications by authors named "Rifang Lan"
Article Synopsis
- The neuroendocrine-immune (NEI) network is crucial for maintaining health, but the interaction between microRNAs (miRNAs) and transcription factors (TFs) within this network needs further exploration.
- Researchers created a NEI-related miRNA-TF regulatory network (NEI-miRTF-N) to analyze immune signaling molecules and how signals may flow from the nervous and endocrine systems to the immune system.
- Disease-specific versions of this network were developed for conditions like depression, Alzheimer's, and dilated cardiomyopathy, utilizing innovative methods to identify key regulatory pathways that could inform new treatment strategies.
Transcription factors are a specialized group of proteins that play important roles in regulating gene expression in human. These proteins control the transcription and translation of genes by binding to specific sites on DNA, thereby regulating key biological processes such as cell differentiation, proliferation, immune response, and neural development. Moreover, transcription factors are also involved in apoptosis and the pathogenesis of various diseases.
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