Prevention of pre-eclampsia with aspirin: A systematic review of guidelines and evaluation of the quality of recommendation evidence.

Background: Evidence has shown significant benefits of aspirin for preventing pre-eclampsia.

Objectives: The objective of this study was to systematically review recommendations from clinical practice guidelines and other recommendation documents on aspirin for the prevention of pre-eclampsia.

Search Strategy: Ten databases were searched for statements from December 1, 2013, to January 1, 2022.