Effect of photodynamic therapy with 5-aminolevulinic acid and EDTA-2Na against mixed infection of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa.

Background: The increasing abundance of drug-resistant bacteria is a global threat. Photodynamic therapy is an entirely new, non-invasive method for treating infections caused by antibiotic-resistant strains. We previously described the bactericidal effect of photodynamic therapy on infections caused by a single type of bacterium.

Mathematical modelling for antimicrobial photodynamic therapy mediated by 5-aminolaevulinic acid: An in vitro study.

Background: Antimicrobial photodynamic therapy (aPDT) using aminolaevulinic acid (ALA) is a promising alternative to antibiotic therapy. ALA administration induces protoporphyrin IX (PpIX) accumulation in bacteria, and light excitation of the accumulated PpIX generates singlet oxygen to bacterial toxicity. Several factors, including drug administration and light irradiation conditions, contribute to the antibiotic effect.

[Continuous Interstitial Subcutaneous Fluid Glucose (ISFG) Measurement during Pre- and Intraoperative Periods for Highly Invasive Surgery].

Background: Recently ERAS protocol has become common, and patients in our hospital drink preoperative oral fluid with carbohydrate nutrition. The present study evaluates interstitial subcutaneous fluid glucose (ISFG) with CGMS-Gold and ISFG variability is relevant to oral fluid.

Methods: The data was ISFG measurement with CGMS-Gold from 29 patients undergoing esophagus operation, liver resection, and pancreaticoduodenectomy in September 2011 to September 2012.

[Perioperative Management of a Patient with Hereditary Angioedema: A Case Report].

Hereditary angioedema (HAE) is a very rare disease that occurs in about 1 in 50,000 to 150,000 people. HAE is caused by low levels or inproper function of the plasma protein C1 inhibitor (C1-INH) which regulates activation of the complement system and the coagulation system. The typical symptom of HAE is regional swellings without pain nor itching, usually triggered by physical trauma or emotional stress.

[Retrospective analysis of perioperative cardiovascular complications in patients with low left ventricular function undergoing noncardiac surgery].

Background: Regarding patients for noncardiac surgery with low left ventricular function, we have little information about perioperative cardiovascular complications, making it difficult to evaluate such patients preoperatively and to inform them of their perioperative course.

Methods: We retrospectively investigated the patients undergoing noncardiac surgery under general anesthesia in our hospital from January 2008 to December 2011. The subjects were 52 patients with low left ventricular function defined as left ventricular ejection fraction under 40%.