Synopsis of recent research by authors named "Rie Sumii"
- Rie Sumii's research primarily focuses on the structural biology of various dehydrogenase enzymes, utilizing X-ray crystallography to elucidate their mechanisms and interactions with coenzymes and inhibitors.
- Significant findings include the detailed characterization of rabbit L-gulonate 3-dehydrogenase and its dual role as a catalytic enzyme and a lens protein, providing insights into its structural domains and their functions.
- The research also emphasizes the selectivity of human 20alpha-hydroxysteroid dehydrogenase for specific inhibitors and the structural differences among related enzymes, contributing to a better understanding of substrate specificity and enzyme regulation.*
