Publications by authors named "Rie McGrail"
Article Synopsis
- Regular measurement of prothrombin time (PT) as an international normalized ratio (INR) is crucial for the safe use of warfarin, and the microINR portable coagulometer was evaluated by SKUP for this purpose.
- The study involved 186 patients and compared results from a standard laboratory method to the microINR device, revealing an imprecision of 6% for INR values ≥2.5 and meeting accuracy standards, but not the imprecision requirement.
- User-friendliness of the device's manual was rated as intermediate, while operating conditions were deemed unsatisfactory, but time efficiency was considered satisfactory.
Using functional haemostasis assays, we demonstrated important differences in stability of direct oral anticoagulants (DOACs) in citrated whole blood and plasma from DOAC treated patients. Laboratories and clinicians should take this into consideration and adjust clinical practices accordingly.
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