[Alphacor keratoprosthesis: device, surgical technique and clinical outcomes].

Purpose: Clinical evaluation of Alphacor keratoprosthesis in patients at high risk of corneal allograft rejection.

Design: Retrospective case series.

Patients And Methods: Alphacor implantation was performed via a two-step procedure with intrastromal insertion followed by secondary exposure of the optic after 6 months.

[Kyrieleis arteritis: report of two cases and literature review].

We report the cases of two patients presenting with unilateral Kyrieleis arteritis complicating severe posterior uveitis, one secondary to toxoplasmosis and the other in the context of Behçet's disease. The treatment response was favorable with complete visual recovery in both cases. Kyrieleis arteritis has been described since 1933, but its pathogenesis is still unknown.

[New therapeutic approach of keratoconus with intracorneal ring segments aided by femtosecond laser (Tecnolas Perfect Vision): indications, operating technique and results].

Objective: To assess the results of intracorneal ring segment implantation assisted by the Tecnolas Perfect Vision(®) femtosecond laser (Heidelberg, Germany).

Settings: Retrospective observational study.

Methods: The patients were operated on with the Tecnolas Perfect Vision(®) femtosecond laser.

Inhibition of corneal neovascularization after alkali burn: comparison of different doses of bevacizumab in monotherapy or associated with dexamethasone.

Background: To compare the effects of different doses of bevacizumab with both saline and dexamethasone on inflammatory angiogenesis in the rat cornea induced by small chemical lesions.

Methods: Corneal chemical cauterization was performed on 24 rats. Animals were divided randomly into six groups and received a daily subconjunctival injection for 7 days of: balanced salt solution 0.

[Optical coherence tomography in following up papilledema in idiopathic intracranial hypertension treated with lateral sinus stent placement].

Objective: To quantify the course of papilledema using the OCT 3 Stratus (Carl Zeiss Meditec, Dublin, CA, USA) after lateral sinus stent placement in patients with idiopathic intracranial hypertension (IIH).

Methods: Ten consecutive patients with a diagnosis of IIH underwent OCT examination before and after lateral sinus stenting, between March 2006 and April 2008, in Timone Hospital's Ophthalmology Department (Marseille, France). All patients had criteria for IIH (International Headache Society, 2004) and sinus abnormalities were diagnosed using three-dimensional rotational gadolinium-enhanced MR venography.

[New approach for determining the damage level of biological tissues using femtosecond laser: advantages and application to corneal surgery].

Introduction: Optimization of femtosecond laser characteristics in corneal surgery is still needed to improve clinical results. In this study, we describe an original characterization technique able to measure laser damage of corneal tissues precisely and to provide complementary physical results on the laser-matter interaction.

Method: A femtosecond laser was used to damage corneas not suitable for graft.

Femtosecond laser-assisted decagonal penetrating keratoplasty.

Purpose: To assess the use of a new polygonal trephination pattern for penetrating keratoplasty (PK) assisted by femtosecond laser.

Design: Prospective, nonrandomized clinical study.

Methods: Sixteen eyes underwent decagonal PK.

Optic nerve compression by an intraorbital megadolichoectatic ophtalmic artery.

A 47-year-old woman, physically active, presented with a history of progressive isolated right eye visual loss (20/200). Ophtalmological examination with Goldmann's perimetry showed a Marcus Gunn pupil, an optic disc temporal pallor and a central scotoma on the affected eye. CT scan and cerebral angiography demonstrated an abnormally wide and elongated (megadolichoectatic) intraorbital ophthalmic artery responsible for optic nerve compression in the optic canal.

[Spectral-domain optical coherence tomography in anterior segment imaging: the 3rd dimension].

Purpose: Anterior segment imaging using optical coherence tomography (OCT) time domain technology has been used for many years. When it appeared, it was a promising technique in the analysis of the anterior segment, making it possible to reach a definition of the ocular structures comparable with histology. Now with new-generation OCT, it is possible to perform high-definition and three-dimensional imaging.

[Subretinal hemorrhage after intravitreal injection of anti-VEGF for age-related macular degeneration: a retrospective study].

Introduction: Prescription of anti-VEGF treatments have increased substantially over the past few years in treatment of wet age-related macular degeneration. We report the occurrence of macular hemorrhages after one year of use of anti-VEGF intravitreal injections, mainly for subfoveal choroidal neovascularization.

Material And Methods: Four hundred forty five injections were given over one year (from 15 March 2007 to 15 March 2008), for age-related macular degeneration, retinal vascular occlusion, diabetic retinopathy, neovascular glaucoma, and idiopathic macular choroidal neovascularization; distributed as follows: 11.

[Arcuate keratotomy for postkeratoplasty astigmatism by femtosecond laser].

Objective: Evaluation of the effectiveness of arcuate keratotomy performed with femtosecond laser for correction of postkeratoplasty astigmatism.

Methods: This retrospective clinical study included 11 eyes. All cases underwent arcuate keratotomy using femtosecond laser.

[A 3T fMRI study of cortical projection of visual scotomas: preliminary results].

Aim: We used functional magnetic resonance imaging (fMRI) to precisely measure both the localization and size of the cortical projections of artificial scotomas in healthy subjects as well as the size of a reversible retinal scotoma in a patient with central serous chorioretinopathy (CSCR).

Methods: Using a 3T MRI scanner, anatomical and functional data were acquired on two healthy subjects and a patient with CSCR. Retinotopic maps were first reconstructed using phase mapping techniques.

Vitrectomy may prevent the occurrence of diabetic macular oedema.

Purpose: This study aimed to demonstrate that vitrectomy may prevent the occurrence of diabetic macular oedema (DMO).

Methods: Three patients with diabetes type 1 underwent vitrectomy in one eye to treat complications of proliferative diabetic retinopathy.

Results: During follow-up, all patients suffered unilateral macular oedema in the non-vitrectomized eye as a result of general metabolic changes.

Correction of postkeratoplasty astigmatism by femtosecond laser compared with mechanized astigmatic keratotomy.

Purpose: To compare the effectiveness of arcuate keratotomy (AK) performed with a femtosecond laser (FSL) or Hanna keratome (Moria, Anthony, France) for correction of postkeratoplasty astigmatism.

Design: Prospective, randomized study.

Methods: This clinical study included 20 eyes.

[Anterior segment analysis using OCT3].

Purpose: Optical coherence tomography has been used for many years, in particular in the field of the retinal imaging, and is a promising technique in the analysis of the anterior segment, providing a similar resolution to histology for ocular tissue.

Material And Methods: We present a collection of images obtained with the OCT3 (Carl Zeiss Meditec, Dublin, CA), with parameters set to obtain good-quality images of the iris and corneal structures.

Results: The OCT provides detailed analysis of the cornea, precise assessment of the dimensions and locations of corneal lesions - in the anterior-posterior plane as well as transversally or obliquely - with 10-microm precision, and the study of the iridocorneal angle and its dynamics.

Short-term results of penetrating keratoplasty performed with the Femtec femtosecond laser.

Purpose: To evaluate the use of the Femtec femtosecond (fs) laser for penetrating keratoplasty (PK) in the treatment of corneal diseases.

Design: Prospective, nonrandomized clinical study.

Methods: Nine eyes of nine patients underwent surgery for PK.

Corneal endothelial cell loss after cataract extraction by using ultrasound phacoemulsification versus a fluid-based system.

Purpose: To compare in vivo corneal endothelial cell loss (ECL) after fluid-based versus ultrasound phacoemulsification.

Methods: In this prospective randomized study, 2 groups of 21 patients underwent phacoemulsification with ultrasound (group 1) or a fluid-based system (group 2). A "divide and conquer" method with capsular bag lens implantation was performed.

[Retinotopic organization of the human visual cortex: a 3T fMRI study].

Unlabelled: INTRODUCTION. We used high-field (3T) functional magnetic resonance imaging (fMRI) to map the retinotopic organization of human cortical areas.

Methods: Retinotopic maps were reconstructed using existing mapping techniques.

[Femtosecond-assisted anterior lamellar keratoplasty].

Introduction: Automated lamellar keratoplasty remains a challenging surgical technique because of surgical difficulties and is associated with a high rate of complications. The precision of the corneal cut at any corneal depth with the femtosecond laser is an important improvement in this technique. We report the first case of femtosecond-assisted anterior lamellar keratoplasty.

[Internal carotid artery dissection on arterial fibromuscular dysplasia causing a central retinal artery occlusion: a case report].

Introduction: We report a case of a 66-year-old woman presenting a central retinal artery occlusion with no cardiovascular risk factor, with assessment using supra-aortic artery ultrasonography showing total internal carotid artery thrombosis.

Observation: When vascular thrombosis risk factors are absent, more in-depth assessment such as a supra-aortic artery angioscan can provide the diagnosis of arterial dissection on arterial fibromuscular dysplasia.

Conclusion: Central retinal artery occlusion is a rare but severe pathology.

[Bilateral corneal endothelial decompensation after postsepticemia coma].

We report a case of unexplained bilateral corneal endothelial decompensation after a coma. A 71-year-old man with no medical history presented with bilateral endothelial decompensation that required penetrating keratoplasty of the left eye combined with cataract surgery. This coma was caused by septicemia originally due to staphylococcus infection following catheter placement in preparation for a CT scan.

Semi-automated detection of the foveal avascular zone in fluorescein angiograms in diabetes mellitus.

Background: The foveal avascular zone (FAZ) is known to enlarge in diabetic retinopathy. In a preliminary study, the authors applied a region growing algorithm to fluorescein angiograms to detect the FAZ in a semi-automated fashion.

Methods: The FAZ in 44 fluorescein angiograms of 44 eyes of 41 patients with diabetic retinopathy underwent manual outlining, then analysis with the region growing function of the ENVI image analysis software.

Metabolic factors and the foveal avascular zone of the retina in diabetes mellitus.

Aim: To study the foveal avascular zone (FAZ) of the central retina in diabetic patients with retinopathy having undergone metabolic evaluation.

Methods: One hundred and ten digital fluorescein angiograms were chosen from our digital image bank after cross matching diabetic patient lists of the ophthalmology and endocrinology departments of our institution. The patients had undergone day visits with systemic, biological and ophthalmologic evaluation, including digital fluorescein angiography.