Publications by authors named "Ridhima Kapoor"

Purpose: Shared decision-making (SDM) is a method for a patient and physician to cooperatively consider a diagnostic or therapeutic option, ultimately empowering the patient to make an informed decision. Atrial fibrillation (AF) ablation is a procedure that would benefit from SDM given the risk of serious adverse events, the high rate of arrhythmia recurrence, and alternative treatment options. Implementing a patient decision aid (PDA) may help facilitate AF ablation SDM by succinctly conveying important information to patients.

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Background: Food insecurity and hunger are global concerns further exacerbated by the unprecedented COVID-19 pandemic. There is a need to understand the depth of this impact, especially among smallholder farmers, and recognize specific coping strategies that offered resilience to inform preparedness in future. The present cross-sectional study assessed the impact of the second wave of COVID-19 pandemic on different dimensions of food security among smallholder farmers of Ho indigenous community of Jharkhand, India.

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In India, indigenous communities are nutritionally vulnerable, with indigenous women suffering the greater burden. Studies and surveys have reported poor nutritional outcomes among indigenous women in India, yet systematic documentation of community-specific nutrition data is lacking. We conducted a narrative review of 42 studies to summarise the nutritional profile of indigenous women of India, with details on their food and nutrient intakes, dietary diversity, traditional food consumption and anthropometric status.

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Article Synopsis
  • Tyrosine kinase inhibitors (TKIs), especially ibrutinib, are commonly used to treat blood cancers, but there are concerns about arrhythmias associated with these medications.
  • A study analyzed 193 patients on long-term cardiac monitoring, revealing that those on ibrutinib had a significantly higher occurrence of atrial fibrillation and non-sustained ventricular tachycardia compared to those on other TKIs or non-TKI treatments.
  • The findings suggest that 25% of ibrutinib patients had to pause their treatment due to arrhythmias, highlighting the need for careful heart monitoring in patients receiving this type of therapy.
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  • Structural changes in the left atrium modestly predict outcomes for patients undergoing catheter ablation for atrial fibrillation (AF), and machine learning (ML) can enhance predictive models using CT scans and patient data.
  • A study analyzed 321 patients who had pre-ablation CT scans, combining morphological features and clinical data to train ML models to classify responders to AF ablation.
  • Results showed that the ML model that integrated various data types significantly outperformed those relying on single data sources, indicating potential for personalized patient management strategies in AF treatment.
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Background: Many indigenous communities reside in biodiverse environments replete with natural food sources but show ​poor access and utilization.

Methods: To understand the links between indigenous food access, dietary intakes, and biomarkers, we conducted a cross-sectional study among women of the Santhal Community (n = 211) from 17 villages in the Godda district of Jharkhand, India. Survey methods included household surveys, dietary intake assessment (24 HDR) and micronutrient and inflammatory biomarkers' estimation.

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Many indigenous foods are nutrient-rich but are often underutilized even among populations at high risk of malnutrition. The aims of this study were to conduct value chain analysis of one cultivated crop (finger millet among the Munda tribe) and one wild green leafy vegetable (Koinaar leaves among the Sauria Paharia tribe) of two Indigenous communities in Jharkhand state, India and to identify entry points for interventions aimed at supporting production and consumption. Semi-structured interviews were conducted with stakeholders among each tribal group and transcripts were open coded and organized based on key themes across the steps of the value chain for each food independently.

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Article Synopsis
  • Tyrosine kinase inhibitors (TKIs) are commonly used for treating various cancers, but they may lead to serious cardiovascular issues, particularly ventricular arrhythmias (VAs), which are not well-studied compared to other heart conditions.
  • A review of five patient cases from 2019 to 2022 found that VAs occurred in individuals with different heart health backgrounds, and these issues improved after stopping TKI therapy, although some needed additional heart medications or devices.
  • The study emphasizes the importance of recognizing the risk of VAs from TKIs in cancer patients and suggests the need for better monitoring and treatment methods to manage these potential cardiovascular side effects.
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Background: Indigenous people globally experience poor nutrition outcomes, with women facing the greater burden. Munda, a predominant tribe in Jharkhand, India, live in a biodiverse food environment but yet have high levels of malnutrition.

Objectives: To assess diets and the nutritional status of Munda tribal women and explore associations with their Indigenous food consumption, dietary diversity, and socioeconomic and demographic profiles.

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Article Synopsis
  • Machine learning is being explored to enhance atrial fibrillation management post-catheter ablation, focusing on predicting patient outcomes using electrograms and ECGs rather than traditional clinical scores.
  • A study involving 156 patients showed that a convolutional neural network could better predict atrial fibrillation recurrence, with an area under the curve (AUROC) of 0.731 for electrograms and 0.767 for ECGs.
  • The best results came from a multimodal fusion model that combined all data sources, achieving an AUROC of 0.859, significantly outperforming the conventional methods.
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Climate change poses severe threats to the social, cultural, and economic integrity of indigenous smallholder subsistence farmers, who are intricately linked with their natural ecosystems. Sauria Paharia, a vulnerable indigenous community of Jharkhand, India, are smallholder farmers facing food and nutrition insecurity and have limited resources to cope with climate change. Eighteen villages of Godda district of Jharkhand inhabited by Sauria Paharia community were randomly selected to conduct a mixed methods study.

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  • Surgical ablation for atrial fibrillation (AF) shows variable success rates, prompting a study to assess how different endocardial lesions post-surgery affect AF relapse in patients.* -
  • In a cohort of 81 patients, high-density mapping revealed reconnection issues in pulmonary veins and the posterior wall, with a significant 56.3% experiencing AF recurrence, particularly in those with longstanding AF and associated low-voltage zones.* -
  • Tailored endocardial ablation targeting specific sites led to a 1-year arrhythmia freedom rate of 81%, highlighting the importance of localized mechanisms and low-voltage zones in determining AF recurrence following surgical procedures.*
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India is endowed with several indigenous foods (IFs), that hold special cultural significance among local and ethnic caommunities, yet no attempts have been made till date to systematically compile their nutritive values. As per FAO's recent mandate on creation of " IFs have received renewed global recognition for their potential to contribute to improved food security while enhancing biodiversity across the world. Hence, the useful properties of wild IFs require proper study and documentation in order to bridge the gap between scientific evidence generation and indigenous peoples' ancestral knowledge.

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The COVID-19 pandemic has globally jeopardized food security, with heightened threats for the most vulnerable including smallholder farmers as well as rural, indigenous populations. A serial cross-sectional study was conducted to document effect of COVID-19 pandemic on food environment, agricultural practices, diets and food security, along with potential determinants of food systems resilience, among vulnerable smallholder farmer households in indigenous communities of Santhal, Munda, and Sauria Paharia of Jharkhand state, India. Telephonic household surveys were conducted in two phases i.

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This study aimed to document the method standardisation and assessment of micronutrient and inflammatory markers in women from indigenous tribal communities of Jharkhand using a low-volume, high-throughput assay. This cross-sectional study was done among women of the reproductive age group from Sauria Paharia and Santhal tribal households (HH) in selected villages. Capillary blood samples were collected from the women during a HH survey to estimate ferritin, soluble transferrin receptor, retinol binding protein 4 and inflammatory biomarkers, C-reactive protein (CRP) and -1-acid glycoprotein (AGP) using a multiplex assay.

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Article Synopsis
  • Ibrutinib, a medication for blood cancers, is linked to higher rates of atrial fibrillation (AF) and other heart rhythm issues, but there’s limited data on its effects on other types of arrhythmias.* -
  • A study analyzed records of 72 patients using event monitors while on ibrutinib, revealing significant occurrences of supraventricular tachycardia, AF, and ventricular tachycardia, with 25% requiring treatment interruptions.* -
  • The findings highlight a concerning prevalence of heart rhythm problems among patients on ibrutinib, suggesting a need for better diagnostic and management approaches for these side effects.*
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The epidemiological necessity for distancing during the COVID-19 pandemic has resulted in postponement of non-emergent hospitalizations and increase use of telemedicine. The feasibility of virtual antiarrhythmic drug (AAD) loading specifically with digital QTc electrocardiographic monitoring (EM) in conjunction with telemedicine video visits is not well established. We tested the hypothesis that existing digital health technologies and virtual communication platforms could provide EM and support medically guided AAD loading for patients with symptomatic tachyarrhythmia in the ambulatory setting, while reducing physical contact between patient and healthcare system.

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Indigenous food (IF) systems, derived from natural ecosystems are perceived to be sustainable and nutritionally adequate. Mundas, an indigenous tribal community in Jharkhand India, are surrounded by rich agroforestry resources, yet display high levels of malnutrition. Our study explored the food environment of Munda community, different IFs they accessed, levels of utilization of IFs in routine diets, their nutritional attributes and factors influencing IF consumption.

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Like several indigenous populations, Sauria Paharias, a vulnerable indigenous tribal group residing in a biodiverse environment of Jharkhand, India, have high levels of undernutrition. We assessed agroforestry and dietary diversity, food consumption especially indigenous food (IF) intake and nutritional status of Sauria Paharia women through a cross-sectional study conducted in 18 villages of Godda district, Jharkhand. Household level information was elicited through household surveys including a dietary survey and a food frequency questionnaire.

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Indigenous food systems of traditional communities are potentially sustainable, have nutrient rich food sources and can enhance dietary diversity. Sauria Paharias, are one of the particularly vulnerable tribal groups of Jharkhand India, who despite residing in rich biodiverse environment and possessing traditional ecological knowledge, lag behind various health, and nutritional indicators. Our study explored their traditional ecological knowledge around indigenous foods (IFs), their routine consumption, access, and nutritive values.

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Background: Inaccurate arrhythmia classification by implantable cardioverter-defibrillators (ICDs) contributes to inappropriate shocks and increased health care utilization.

Objective: The purpose of this study was to evaluate the ability of a novel discriminator using far-field (FF) and near-field (NF) right ventricular lead electrograms (EGMs) to differentiate ventricular tachycardia (VT) from supraventricular tachycardia (SVT) in patients with underlying conducted narrow QRS, right bundle branch block (RBBB), and left bundle branch block (LBBB).

Methods: ICD interrogations were reviewed, identifying subjects with tachycardia events at least 5 beats in duration with stable morphology and cycle length.

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