Ultrasound-assisted extraction, optimisation using response surface methodology and HPLC-DAD phenolic compounds quantification from S. peels cultivated in Tunisia.

A new ultrasound-assisted extraction method was developed for the determination of phenolic compounds extracted from peels cultivated in Tunisia. Several extraction variables including: extraction time, temperature, liquid/solid ratio and pH have been studied using response surface methodology. The extraction efficiency was evaluated by measuring the total phenolics; flavonoids and antioxidants content.

Effect of geographical origin on the chemical characteristics of acorns: profiling fatty acids, tocopherols, and phenolic composition.

The impact of geographical origin on the chemical composition of acorns from Quercus species has significant attention. This study aimed to explore the phenolic composition of methanolic extracts, tocopherol content, and fatty acid composition of acorn oils from six different populations of acorns. The obtained results revealed that acorn oil from BniMtir exhibited high levels of α-tocopherol (58 mg/kg).

Mono or double Pd-catalyzed C-H bond functionalization for the annulative π-extension of 1,8-dibromonaphthalene: a one pot access to fluoranthene derivatives.

The Pd-catalyzed annulative π-extension of 1,8-dibromonaphthalene for the preparation of fluoranthenes in a single operation has been investigated. With specific arenes such as fluorobenzenes, the Pd-catalyzed double functionalization of C-H bonds yields the desired fluoranthenes. The reaction proceeds via a palladium-catalyzed direct intermolecular arylation, followed by a direct intramolecular arylation step.

Chemical Composition and Bioactivities of Quercus canariensis Flour Acorns Extracts Growing in Tunisia.

The current study was conducted to investigate the chemical composition of Quercus canariensis flour acorns extracts as well as its biological activities in regards to the growing area using spectrophotometric and chromatographic techniques. The phenolic profile was composed of 19 compounds identified through HPLC-DAD analysis. Coumarin was the most abundant compound quantified in BniMtir, Nefza and ElGhorra and gallic (12.

Antibacterial, antibiofilm and cytotoxic properties of prodigiosin produced by a newly isolated Serratia sp. C6LB from a milk collection center.

The aim of this work was to produce a red tripyrrole pigment prodigiosin from Serratia sp. C6LB strain, to investigate the promising antimicrobial properties on Gram-positive and Gram-negative bacterial strains. The research was also proposed to evaluate the antibiofilm activity on Staphylococcus epidermidis S61 biofilm and its cytotoxic activity against human cancer cell lines.

Tunisian Native L. Extracts: Phytochemical Composition and Biological Activities.

Mint species ( family) have been used as traditional remedies for the treatment of several diseases. In this work, we aimed to characterize the biological activities of the total phenolic and flavonoid contents of L. extracts collected from two different regions of Tunisia.

Identification and quantification of phenolic and fatty acid profiles in mill. seeds by LC-ESI-MS and GC: Effect of drying methods on chemical composition.

This study aimed to evaluate Mill. seeds oil as well as methanolic-aqueous extract on fatty acid and phenolic's composition as well as antioxidant activities with regard to the cones drying methods: convection and sun methods. The highest amounts of total phenols (14.

Desf. roots extract: LC-ESI-MS Analysis, antioxidant activity and gastroprotective effect on experimentally-induced ultrastructural gastric ulcers in mice.

Desf. (Atlas Pistachio) is an Anacardiaceae tree traditionally used in Tunisia for the treatment of ophthalmic, stomatitis, and digestive tract diseases. In the present study, the Desf.

Phenolic profile (HPLC-UV) analysis and biological activities of two organic extracts from Turra roots growing in Tunisia.

Turra subsp. roots was investigated, after extraction with two different solvents: ethanol and ethyl acetate, for its phenolic profile as well as biological activities. Turra subsp.

Chemical modification of lignin derived from spent coffee grounds for methylene blue adsorption.

In this work, spent coffee grounds (SCG) were treated using sulfuric acid hydrolysis in order to isolate the sulfuric acid lignin (SAL). The reactivity of SAL was improved through phenolation and acetylation. Spectroscopic analysis showed that the isolated lignin is composed of GHS type and it was characterized by a high amount of (C-C) and β-O-4 bonds.

Change in some quality parameters and oxidative stability of olive oils with regard to ultrasound pretreatment, depitting and water addition.

Ultrasound pretreatment with different times (0, 4, 8, 10 min) on olive paste previous malaxation of olive oil extraction along with depitting and water application procedures were studied. The effects of these procedures on oil yield, quality parameters and oxidative stability have been studied. Therefore, the olive oil yield increase with increasing time of ultrasound treatment.

Reactivity of bromoselenophenes in palladium-catalyzed direct arylations.

The reactivity of 2-bromo- and 2,5-dibromoselenophenes in Pd-catalyzed direct heteroarylation was investigated. From 2-bromoselenophene, only the most reactive heteroarenes could be employed to prepare 2-heteroarylated selenophenes; whereas, 2,5-dibromoselenophene generally gave 2,5-di(heteroarylated) selenophenes in high yields using both thiazole and thiophene derivatives. Moreover, sequential catalytic C2 heteroarylation, bromination, catalytic C5 arylation reactions allowed the synthesis of unsymmetrical 2,5-di(hetero)arylated selenophene derivatives in three steps from selenophene.

Gold-Catalyzed Suzuki Coupling of ortho-Substituted Hindered Aryl Substrates.

A method that allows hindered ortho-substituted aryl iodides to be efficiently coupled to phenylboronic acid using a gold-catalyzed C-C bond formation is presented. The use of a molecularly-defined dinuclear gold chloride catalytic precursor that is stabilized by a new tetradentate (N,N')-diamino-(P,P')-diphosphino ferrocene hybrid ligand in a Suzuki-type reaction is described for the first time. Electron-rich isopropyl groups on phosphorus were found essential for a superior activity, while the performances of a set of analogous gold dinuclear complexes that were fully characterized by multinuclear NMR spectroscopy and XRD analysis, were investigated.

Unprecedented Access to β-Arylated Selenophenes through Palladium-Catalysed Direct Arylation.

Several reported methods allow access to α-arylated selenophenes, whereas the synthesis of β-arylated selenophenes remains very challenging. Here, the Pd-catalysed coupling of benzenesulfonyl chlorides with selenophenes affording regiospecific β-arylated selenophenes is reported. The reaction proceeds with easily accessible catalyst, base and substrates, and tolerates a variety of substituents both on the benzene and selenophene moieties.

Phenolic content, antioxidant capacity and antimicrobial activity of leaf extracts from Pistacia atlantica.

The aim of this study was to investigate the secondary metabolites related to Pistacia atlantica Desf as well as their biological activities. Results show that using ethanol as a solvent exhibited the highest content of total phenolics and flavonoids (68.23 mg GAE g of DW and 44 mg RE g of DW), followed by aqueous one (20.

Effect of storage on refined olive oil composition: stabilization by addition of chlorophyll pigments and squalene.

Refined olive oil has been analyzed in order to evaluate the influence of storage time on their quality after enrichment with chlorophyll pigments and squalene. At the end of the storage, chlorophyll pigments decomposed for more than 90%, while, carotene pigment loss was lower showing up to 75% in all oil samples stored at 20°C and 50°C. The reduction of total phenolic compounds exhibited similar degradation profiles, reducing by 81% for enriched refined olive oil stored at 20°C and 50°C after six months.

3-Amino-4-(1,3-benzoxazol-2-yl)-5-(cyclo-hexyl-amino)-thio-phene-2-carbo-nitrile.

In the title compound, C18H18N4OS, the cyclo-hexyl ring adopts a chair conformation. The other rings of this compound lie almost in the same plane, with a mean deviation of 0.03 (2) Å from the least-squares plane defined by the 14 constituent atoms.

Recovery of hydroxytyrosol rich extract from two-phase Chemlali olive pomace by chemical treatment.

Unlabelled: A very simple method is proposed to produce hydroxytyrosol, a commercially unavailable compound with well-known biological properties which justify a potential commercial application. The 2-phase Chemlali olive pomace is selected as substrate for chemical treatment. Different conditions of chemical treatment, including concentration of acid and alkaline solutions, time and temperature, were assayed.

Analytical evaluation of two monovarietal virgin olive oils cultivated in the south of Tunisia: Jemri-Bouchouka and Chemlali-Tataouin cultivars.

Background: The characterisation of virgin olive oils from two Tunisian cultivars, growing in the Tataouin zone, namely Jemri-Bouchouka, a rare olive cultivar, and Chemlali-Tataouin, was carried out. Several analytical parameters were evaluated; these include quality index, fatty acids, phenolic, chlorophyll, carotenoid, squalene, α-tocopherol compositions and oxidative stability.

Results: Jemri-Bouchouka olive oil had the highest value of oleic acid (74.

Influence of physico-chemical treatment on the subsequent biological process treating paper industry wastewater.

The present paper presents the main results of the biodegradation study of paper industry wastewater through physico-chemical treatment. Indeed, around 60% of chemical oxygen demand (COD) removal can be achieved by electroflocculation treatment. Furthermore, a removal efficiency of the COD of almost 91% has been obtained by biological treatment, with activated amount of sludge for 24 h of culture.

Phenolic composition, isolation, and structure of a new deoxyloganic acid derivative from Dhokar and Gemri-Dhokar olive cultivars.

Two rare olive cultivars, Dhokar and Gemri-Dhokar, growing in the south of Tunisia were investigated to identify their phenolic profile and evaluate their sugar content and antioxidant activity. The highest value of phenolic content was detected in Gemri-Dhokar cultivar extract (6.97 g gallic acid equivalents/kg of fresh olive).

Ultrasonic activation of Heck type reactions in the presence of Aliquat-336.

Without phosphine and base, palladium catalysts such as PdCl(2), Pd(OAc)(2) and PdCl(2)(PhCN)(2) in water/DMF mixtures with Aliquat-336 proved to be excellent catalytic systems for Heck reactions involving several aryl bromides with styrene and acrylic compounds. Yields are remarkably improved under ultrasonic irradiation and the products show a high purity.