Publications by authors named "Rico-Martinez G"

Microwave ablation is commonly used in soft tissue tumors, but its application in bone tumors has been barely analyzed. Antennas to treat bone tissue (~3 cm2), has been lately designed. Bone tumors at pathological stage T1 can reach 8 cm wide.

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Background: The reconstruction of the proximal humerus is possible from the resection of the tumor and the placement of a prosthesis. In some cases, they do not meet the anthropometric aspects of the patients.

Objective: To determine the parameters to size the components of a humeral prosthesis and the development of a set, using design software.

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Osteosarcoma is the most common malignant bone tumor. Early diagnosis remains a major challenge, mainly because of the lack of specific biomarkers. We performed miRNAs expression analysis through qPCR in affected and paired healthy bone derived from osteosarcoma patients.

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Osteosarcoma is the most common malignant bone neoplasia affecting individuals in the second decade of life. The survival rate has not been improved during the last 25 years, in part because of the lack of specific markers. The microRNAs have been identified as important regulators of gene expression, experimental evidence suggests these molecules as key players in cancer development and progression.

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The frequency of giant cell tumors reported in the literature is very variable. Considering that our population has its own features, which distinguish it from the Anglo-Saxon and Asian populations, we think that both the frequency and the clinical characteristics of giant cell tumors in our population are different. The major aim of this paper was to determine the frequency and clinicopathological characteristics of giant cell tumors of the bone.

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The dedifferentiated giant-cell tumor of the bone is a very rare variant of the giant-cell tumor (GCT). We report the clinical, radiographic and histological findings of a dedifferentiated GCT in which the dedifferentiated component consisted of small round cells. We also comment on previously reported cases of dedifferentiated GCT, discuss the clinical implications of this dual histology, and analyze the information published about the coexistence of similar genetic abnormalities in GCT and small round cell tumors of the bone.

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INTRODUCTION. Previously, amputation was the only treatment option for patients with malignant bone tumors. Due to technological, medical and surgical advances, the number of survivors and years of survival has been increasing, and thus, the interest in evaluating the impact of this disease on quality of life.

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Giant cell tumor (GCT) is an aggressive benign neoplasia that accounts for 5% of primary bone tumors and 20% of all benign bone tumors. It appears almost exclusively after skeletal maturation, between 20 and 40 years of age, and is predominant among females. We report the case of a 39 year-old male patient who in 1988 sustained a left hip fracture in a pathological area.

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Objective: To assess the functional efficacy of the RIMAG unconventional hip prosthesis in cancer and non-cancer patients.

Material And Methods: Functional analysis of 38 patients with RIMAG arthroplasty, using the Musculoskeletal Tumor Society Scoring System and including the following: functionality versus histologic diagnosis (5 malignancies, 3 metastases, 14 giant cell tumors (GCT), 8 with other benign tumors, and 8 had no tumor), age (40.4 +/- 19.

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Introduction: Conservative surgery and reconstruction with an unconventional prosthesis are indicated for tumors of the humerus without neurovascular compromise, as they help preserve shoulder, elbow and hand function. The humerus is the third most frequent site of benign, aggressive, malignant and metastatic tumors that cause functional limitation or limb loss.

Material: Patients with a bone tumor of the humerus without neurovascular involvement that met the inclusion criteria.

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Introduction: Chondrosarcoma is a malignant tumor of chondroid matrix-producing cells; based on its frequency, it is the second most common malignant bone tumor (10-20%) and responds poorly to chemo- and radiotherapy. It is infrequent in the pelvis. It has a rapid growth potential.

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Osteosarcoma is the most common primary high-grade bone tumor in both adolescents and children. Early tumor detection is key to ensuring effective treatment. Serum marker discovery and validation for pediatric osteosarcoma has accelerated in recent years, coincident with an evolving understanding of molecules and their complex interactions, and the compelling need for improved pediatric osteosarcoma outcome measures in clinical trials.

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Surgical management of tumors located in the spine and the pelvis involves greater difficulty. Moreover, these tumors are usually very large and vascularized. Preoperative embolization of the internal iliac artery is a relatively safe procedure that may reduce the risk of bleeding and local recurrence in the case of benign tumors.

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Introduction: Benign fibrous histiocytoma is a rare tumor with very stringent radiologic and histopathologic criteria. It accounts for approximately 1% of all the benign bone tumors. It may be located in both the soft tissues and bone.

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Background: Dedifferentiated chondrosarcomas account for approximately 10% of all chondrosarcomas. There are few reports that describe the cytologic findings in dedifferentiated chondrosarcomas. In all these cases it was only present in the smears as a high grade sarcoma component.

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Introduction: (99m)Tc-tetrofosmin is an efficient agent as a tumor marker. Several studies have proven its efficiency in detection and localization of tumors of the breast, larynx, thyroid, parathyroid glands, lung, brain, skin, lymphatic and musculoskeletal tissues with a sensitivity and specificity of 95% to 100%. It is used as a predictor of therapy efficacy and to localize remaining and recurrent tissue as well as local and distant extension.

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Introduction: We consider of great importance knowing the types of bone tumors and tumor-like lesions in adults and the elderly, which are increasing in proportion in our country.

Objectives: (1) To analyze the frequency of bone tumors and tumor-like lesions in adults and elderly; (2) to determine any difference between these two groups; (3) and to analyze the most frequent sites of involvement.

Material And Methods: We conducted a cross-sectional descriptive study that consisted in a retrolective review of all cases classified as a bone tumor or a tumorlike condition from year 2000-2006.

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Introduction: The objectives of this work were: (1) To determine the prevalence of bone neoplasms and pseudoneoplasms lesions in a group of adolescents (15 to 19 years), (2) To determine the more frequent bone neoplasms and pseudoneoplasms lesions in a group of young adults (29 to 39 years), (3) To determine if there are differences in the frequency of bone neoplasms and pseudoneoplasms lesions between the group of adolescents and the group of young adults and (4) To determine if there is any difference according to gender.

Material And Methods: We conducted a descriptive, cross-sectional study that consisted in the review of the Pathology Department files in the National Institute of Rehabilitation. We included all patients with a histopathologic diagnosis of bone neoplasms or pseudoneoplasms lesion from January 2000 to December 2006 within the age of presentation from 15 to 19 or 20 to 39 years.

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Introduction: Pediatric age is the group mainly affected by bone tumors. The objectives of this work were: (1) To determine which are the bone tumors and pseudotumoral lesions more frequent in the group of age from 0 to 14 years; (2) To determine if there are differences in the frequency of the tumors and pseudotumoral lesions between different subgroups and (3) To determine if there is any difference in the frequency of the different tumors according to gender.

Methods: We conducted a cross-sectional study based on the Pathology files of the National Institute of Rehabilitation.

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The purpose of this paper is to present the orthopedic-oncologic and functional outcomes of internal partial hemipelvectomy for a secondary giant pelvic chondrosarcoma in a patient with multiple hereditary osteochondromatosis.

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Design: Report of cases.

Objective: Review of the cases in a period of 10 years with bone and soft tumors in foot and ankle, to knowing epidemilogical, clinic and patologic anatomy parameters to describe the behavior.

Materials And Methods: Review of 166 cases from 1991 to 2000 and been analyze with descriptive statistic, association measurment for inside stratum, with odds ratio, hipótesis test with chi square for qualitative date and t to Student for quantitative date.

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Background: Low grade fibromyxoid sarcoma, first described in 1987, is a rare sarcoma characterized by a bland and deceptively benign histologic appearance but with aggressive behavior.

Case: A 51-year-old female presented with a history of a recurrent and slowly growing mass in the left foot. Fine needle aspiration biopsy showed an abundant myxoid background with occasional thick bands of collagen.

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