Publications by authors named "Rick M Myers"
Mol Neuropsychiatry
February 2018
Article Synopsis
- Subjects with schizophrenia (SZ) and bipolar disorder (BD) show reduced activity of mitochondrial complex I, particularly in SZ patients, where activity is 45% lower than controls.
- Antipsychotic and antidepressant medications may contribute to this reduced activity, especially in individuals with early-onset symptoms.
- Both SZ and BD patients have increased mitochondrial DNA (mtDNA) copy numbers compared to controls, but the overall burden of a common mtDNA deletion remains unchanged.
