Publications by authors named "Richard Vistelle"
Article Synopsis
- Researchers used Fourier transform infrared microspectroscopy (FT-IRM) to study the changes in brain tissue due to tumors, finding differences in fat content between healthy and tumor-affected areas.
- The study revealed that lipid levels and composition can serve as indicators to distinguish between normal brain tissue and tumors, connecting these changes to important factors influencing neurodegenerative disorders.
- FT-IRM was found to effectively identify specific molecular changes associated with tumor presence, and its results complemented traditional histological techniques for detecting early tissue abnormalities.
Purpose: Comparison of the influence of two different brain tumors (C6 and CNS1 glioma) on methotrexate (MTX) disposition in plasma, brain, and tumor tissue extracellular fluid (ECF).
Methods: Serial collection of plasma samples and brain ECF dialysates after i.v.