FER-1/Dysferlin promotes cholinergic signaling at the neuromuscular junction in C. elegans and mice.

Dysferlin is a member of the evolutionarily conserved ferlin gene family. Mutations in Dysferlin lead to Limb Girdle Muscular Dystrophy 2B (LGMD2B), an inherited, progressive and incurable muscle disorder. However, the molecular mechanisms underlying disease pathogenesis are not fully understood.

Superelastic scattering of electrons from highly charged ions with inner shell vacancies.

We report the measurement of electrons scattered superelastically from highly charged ions having an initial K-shell vacancy. In this process, the scattered electron gains approximately 725 eV of energy from the deexcitation of an excited He-like F7+(1s2s 3S) metastable ion to its ground state. Theoretical calculations based on an R-matrix approach agree well in position, shape, and magnitude with the experimental data.