Influence of uterine manipulator use on the incidence of lymphovascular propagation in the treatment of endometrial cancer.

Background: Endometrial cancers are among the epithelial malignancies of the lining of the uterine cavity. The invasion of carcinoma into the lymphovascular space (LVSI) is considered a risk factor for the course of the disease.

Material And Methods: We evaluated 170 female patients.

Survivin and gynaecological tumours.

Survivin is the smallest member of the inhibitors of apoptosis (IAP) family. However, participation in inhibition of apoptosis is not the only function of this molecule. Survivin can also affect the proper process of mitosis and even promoting of angiogenesis or DNA repair.