Capecitabine-induced ventricular fibrillation arrest: Possible Kounis syndrome.

We report the case of capecitabine-induced ventricular fibrillation arrest, possibly secondary to type I Kounis syndrome. A 47-year-old man with a history of T3N1 moderately differentiated adenocarcinoma of the colon, status-post sigmoid resection, was started on adjuvant capecitabine approximately five months prior to presentation of cardiac arrest secondary to ventricular fibrillation. An electrocardiogram (EKG) revealed ST segment elevation on the lateral leads and the patient was taken emergently to the cardiac catheterization laboratory.

The role of body mass index and diabetes in the development of acute organ failure and subsequent mortality in an observational cohort.

Introduction: Several studies have shown a correlation between body mass index (BMI) and both the development of critical illness and adverse outcomes in critically ill patients. The goal of our study was to examine this relationship prospectively with particular attention to the influence of concomitant diabetes mellitus (DM).

Methods: We analyzed data from 15,408 participants in the Atherosclerosis Risk in Communities (ARIC) study for this analysis.