Publications by authors named "Richard Palyo"
Article Synopsis
- Inter-frame motion in cardiac PET imaging with rubidium-82 can complicate the accurate quantification of myocardial blood flow (MBF) and the diagnosis of coronary artery diseases due to rapid tracer distribution changes.
- The proposed TAI-GAN method uses a generative adversarial network to transform early imaging frames, aligning them with the tracer distribution of later frames, which helps overcome limitations of traditional image registration techniques.
- Evaluations on clinical datasets indicate that TAI-GAN effectively improves the quality of early frames and enhances motion estimation accuracy and MBF quantification when compared to original frames, with the code available for public use.
Article Synopsis
- The study tackles the challenges of inter-frame motion correction in dynamic cardiac PET imaging due to the rapid movement of rubidium-82 (Rb) and varied tracer distribution, particularly during early frames.
- It introduces a new method called the Temporally and Anatomically Informed Generative Adversarial Network (TAI-GAN) that enhances image registration by transforming early frames to match late reference frames using both temporal and anatomical data.
- Validation on a clinical Rb PET dataset showed that TAI-GAN improved image quality and increased accuracy in motion estimation and myocardial blood flow quantification compared to using original early frames.
Unlabelled: There is increasing concern about radiation exposure from myocardial perfusion SPECT (MPS). γ-cameras with solid-state cadmium-zinc-telluride (CZT) detectors have better count sensitivity and spatial resolution than conventional sodium iodine detectors, allowing for significant reductions in radiotracer dose or acquisition time. This study aimed to demonstrate the capability of a hybrid CZT SPECT/64-slice CT system for dose reduction and to determine the maximal reduction possible without compromising image quality or the quantification precision of clinical MPS.
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