Complications of cold hot snare polypectomy of 10-20 mm polyps: A retrospective cohort study.

Background And Aim: Cold snare polypectomy is safe and efficacious for removing polyps <10 mm with reduced rates of delayed postpolypectomy bleeding and postpolypectomy syndrome. This technique can also be used for sessile polyps ≥10 mm; however, further evidence is required to establish its safety. The aim of this study was to compare intraprocedure and postprocedure adverse events in patients who underwent cold (CSP) hot snare polypectomy (HSP) of 10-20 mm sessile colonic polyps.

Cold snare piecemeal EMR of large sessile colonic polyps ≥20 mm (with video).

Background And Aims: Conventional EMR using a hot snare is the standard of care for resection of large (≥20 mm) nonmalignant sessile colonic polyps. Serious adverse events are predominantly because of electrocautery. This could potentially be avoided by cold snare piecemeal EMR (CSP-EMR).

A prospective comparison of cold snare polypectomy using traditional or dedicated cold snares for the resection of small sessile colorectal polyps.

Background And Study Aims:  The evidence for efficacy and safety of cold snare polypectomy is limited. The aim of this study was to assess the completeness of resection and safety of cold snare polypectomy, using either traditional or dedicated cold snares.

Patients And Methods:  This was a prospective, non-randomized study performed at a single tertiary hospital.

Risk stratification of upper GI bleeding with an esophageal capsule.

Background: Analysis of upper GI bleeding (UGIB) presentations to our institutions suggests that many patients admitted for endoscopic investigation could be managed safely as outpatients.

Objective: To learn whether an esophageal capsule could identify a low-risk group of patients with UGIB who could safely wait for elective EGD.

Design: Diagnostic, nonrandomized, single-blind (investigator) study.

SINGLE-01: a randomized, controlled trial comparing the efficacy and depth of insertion of single- and double-balloon enteroscopy by using a novel method to determine insertion depth.

Background: Single-balloon enteroscopy (SBE) was introduced as an alternative to double-balloon enteroscopy (DBE) for the investigation and management of small-bowel conditions. To date, there is only 1 randomized, controlled trial comparing SBE and DBE in a Western population.

Objective: To compare the 2 instruments in a Western population to assess for differences in clinical outcomes and insertion depth (ID).

Thiopurine immunomodulators in ulcerative colitis: moving forward with current evidence.

The goals of treatment for ulcerative colitis (UC) are to induce and maintain corticosteroid-free remission, thereby reducing hospitalizations and surgeries and preventing longer-term disease complications including colorectal cancer. Despite an incomplete evidence base, thiopurine immunomodulators remain a principle therapeutic option for patients failing aminosalicylate monotherapy and requiring multiple courses of corticosteroids. In this review, we outline the current evidence supporting the role of thiopurines in achieving these treatment goals in UC, including discussions of the important safety issues regarding their use.