Publications by authors named "Richard L Kline"
Article Synopsis
- The article examines HIV-1 subtype diversity in the U.S. from 2008-2016, focusing on demographics and risk groups.
- Subtype B was the most prevalent, accounting for 93.6% of cases, while non-B subtypes like C and CRF01_AE saw an increase, especially among women and foreign-born individuals.
- Despite B being dominant, a rise in non-B subtypes highlights potential challenges for clinical management and vaccine development as diversity in infections grows.
Context: During a mass smallpox immunization campaign, vaccine may be exposed to ambient temperatures for extended periods of time.
Objective: To determine the viability of undiluted and 5x diluted DryVax smallpox vaccine after cycling vaccine in and out of refrigeration for 2 weeks, as might occur during an immunization campaign.
Design: Two vials of Dryvax vaccine were reconstituted as per manufacturer's instructions (1x) and two vials were reconstituted using 5x the recommended diluent (5x).
Background: The outbreak of monkeypox in the Midwestern United States during June 2003 marks the first documented human infection in the Western Hemisphere. Consistent with those in outbreaks in Africa, most cases in this outbreak were associated with febrile rash illness. We describe a cluster of monkeypox in a family with a spectrum of clinical illness, including encephalitis, and outline the laboratory confirmation of monkeypox.
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