Publications by authors named "Richard L Chalmers"

Article Synopsis
  • Ulnar collateral ligament (UCL) injuries in the thumb often occur due to sports-related hyper-abduction or falls, and distinguishing between partial and complete tears can be difficult, especially in emergencies.
  • A study was conducted reviewing patients who underwent ultrasound for suspected UCL injuries, finding that ultrasound had a 63% accuracy rate in confirming complete tears compared to surgical findings.
  • While ultrasound is helpful for diagnosing UCL injuries, it has a significant false-positive rate of 37%, suggesting the need for additional imaging techniques to enhance accuracy.
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Background: Cutaneous metastases may cause considerable discomfort as a consequence of ulceration, oozing, bleeding and pain. Electrochemotherapy has proven to be highly effective in the treatment of cutaneous metastases. Electrochemotherapy utilises pulses of electricity to increase the permeability of the cell membrane and thereby augment the effect of chemotherapy.

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The complex biological and physiological mechanisms that result in poor quality scarring are still not fully understood. This review looks at current evidence of the role of transforming growth factor-beta (TGFβ) in this pathological process.

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