Publications by authors named "Richard John Jones"
Article Synopsis
- Haploidentical donors present a promising option for blood or marrow transplantation (BMT), particularly benefiting non-White patients, due to their increased availability.
- A study of 120 patients showed that after 3 years post-BMT, 25% experienced nonrelapse mortality and 27% had disease relapse, with overall survival rates at 56%.
- Significant factors affecting outcomes included older age at BMT, presence of certain genetic mutations, and whether patients had splenomegaly at the time of transplantation.
Transpl Infect Dis
June 2021
Article Synopsis
- Treatment of ganciclovir-resistant cytomegalovirus (CMV) infections in transplant patients is challenging, with cidofovir (CDV) being one of the few options, despite its harmful side effects.
- A study reviewed outcomes in 16 transplant patients treated with CDV, revealing a high rate of complications like nephrotoxicity and uveitis, and 50% failure in clearing CMV DNAemia.
- The findings stress the need for better treatment alternatives due to high mortality rates and significant risks associated with CDV in this patient group.
