Publications by authors named "Richard C San George"
Background: Point-of-care (POC) hemoglobin A1c (HbA1c) testing has advantages over laboratory testing, but some questions have remained regarding the accuracy and precision of these methods. The accuracy and the precision of the POC Afinion™ HbA1c Dx test were investigated.
Methods: Samples spanning the assay range were collected from prospectively enrolled subjects at three clinical sites.
Fingerstick Precision and Total Error of a Point-of-Care HbA1c Test.
J Diabetes Sci Technol
September 2020
Article Synopsis
- - The study focused on assessing the precision and total error of the Afinion™ HbA1c Dx point-of-care (POC) test for diabetes diagnosis using fingerstick and venous blood samples to ensure reliable performance.
- - Fingerstick blood samples were collected from 61 subjects at three different POC sites, and various statistical analyses were done to evaluate repeatability and variance across different operators and instruments.
- - Results showed that the POC test had low total imprecision (around 1.30% to 2.03% CV) and error rates (2.87% to 4.75%) for both sample types, indicating it meets the quality standards for accuracy in diabetes testing.
Background: Serial measurement of natriuretic peptides may guide management in heart failure (HF) patients. In previous trials, natriuretic peptides were infrequently monitored, which may undervalue the benefit of this approach.
Methods And Results: HOME was an adaptive three-arm randomized clinical study to test whether home monitoring of BNP could reduce HF-related death, hospitalization due to acute decompensated HF (ADHF), and ADHF treated with intravenous diuretics in the emergency department or outpatient setting.