Publications by authors named "Richard A Hill"

The pathways regulated in ectomycorrhizal (EcM) plant hosts during the establishment of symbiosis are not as well understood when compared to the functional stages of this mutualistic interaction. Our study used the EcM host Eucalyptus grandis to elucidate symbiosis-regulated pathways across the three phases of this interaction. Using a combination of RNA sequencing and metabolomics we studied both stage-specific and core responses of E.

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This brief review in honor of Douglas Johnson, MD describes the rationales and initial clinical outcomes in studies to date on Trabectome, Glaukos iStent, iScience (canaloplasty), and Solx (suprachoroidal shunt), all newly developed surgical technologies for treatment of open-angle glaucomas. These new approaches to angle surgery have been demonstrated in preliminary case series to safely lower IOP in the mid-teens with far fewer complications than expected with trabeculectomy and without anti-fibrotics. Trabectome and iStent are relatively non-invasive, aim to improve access of aqueous to collector channels and do not preclude subsequent standard surgery.

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This study was undertaken to evaluate the efficiency of a trabecular micro-bypass stent designed to allow direct aqueous drainage from the anterior chamber into Schlemm's canal in patients with glaucoma. In this prospective case series of 6 patients with open-angle glaucoma, the microstent was inserted ab interno under local anesthesia in an ophthalmic operating room. Patients were seen postoperatively at 1 to 2 d, 1 wk, and 1, 2, 6, and 12 mo.

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Purpose: To evaluate the clinical efficacy and safety of the double-plate Ahmed Glaucoma Valve.

Design: Multicenter, retrospective observational case series.

Methods: We reviewed 50 eyes in 50 patients treated with the double-plate Ahmed Glaucoma Valve with mean follow-up of 11.

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Purpose: To describe a surgical technique to improve visualization and surgical access for trabeculectomy and implantation of aqueous drainage devices.

Materials And Methods: After the corneal traction suture (6-0 polygalactin; S-29 needle) is placed, a second suture is passed through Tenon's capsule alone, either at the anterior edge of a limbus-based conjunctival flap for trabeculectomy or at the incisional edge of a fornix-based conjunctival flap for drainage implant surgery.

Results: The incision for limbus-based peritomies must be posterior enough to take advantage of the posterior thickening of Tenon's capsule when placing the traction suture.

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