Sarcopenia is independently associated with diabetic foot disease.

The aim of this study was to investigate the association of sarcopenia and diabetic foot disease (DFD) in a cross-sectional study. Body composition was assessed using dual-energy X-ray-absorptiometry (DXA) among 1105 patients with type 2 diabetes (120 patients with newly diagnosed DFD [DFD duration less than 3 months]). Severity of DFD was assessed, referring to foot ulcers, Wagner grade and the percentage of amputation.

Aldosterone/direct renin concentration ratio as a screening test for primary aldosteronism: A meta-analysis.

Objective: The accuracy of aldosterone/direct renin concentration ratio (ADRR) as a screening test in patients with primary aldosteronism (PA) varies widely across the studies. Therefore, we conducted a meta-analysis to assess the accuracy of ADRR.

Methods: A literature search was performed in PubMed, Embase, and the Cochrane library published between April 1971-February 2016.

Association Between Serum Cortisol and Chronic Kidney Disease in Patients with Essential Hypertension.

Background/aims: Serum cortisol level is elevated in patients with essential hypertension. We aimed at investigating the association of serum cortisol levels with parameters of renal function in essential hypertension.

Methods: One hundred and seventy-eight patients with essential hypertension participated in the study.

Lispro administered by the QS-M Needle-Free Jet Injector generates an earlier insulin exposure.

Objective: The aim of this study is to evaluate the pharmacokinetic and pharmacodynamic (PK-PD) profiles of lispro administered by the QS-M needle-free jet injector in Chinese subjects.

Research Design And Methods: A randomized, double-blind, double-dummy, cross-over study was performed. Eighteen healthy volunteers were recruited.

Serum LBP Is Associated with Insulin Resistance in Women with PCOS.

Introduction: Lipopolysaccharide-binding protein (LBP) is closely associated with many metabolic disorders. However, no study has been done to explore the relationship between LBP and polycystic ovary syndrome (PCOS). The objective of this study was to investigate whether the serum LBP level is elevated and associated with insulin resistance (IR) in PCOS.

Serum bisphenol A as a predictor of chronic kidney disease progression in primary hypertension: a 6-year prospective study.

Objective: Hypertensive nephropathy is one of the major causes of chronic kidney disease (CKD). Bisphenol A (BPA) is associated with elevated blood pressure and urinary albuminuria. The aim of this study is to evaluate the association between serum BPA with the progression of CKD in patients with primary hypertension.

Serum bisphenol A and progression of type 2 diabetic nephropathy: a 6-year prospective study.

Aims: Bisphenol A (BPA) is associated with diabetes and cardiovascular diseases. The aim of our study was to evaluate whether serum BPA could predict the progression of chronic kidney disease (CKD) in patients with type 2 diabetes (T2D).

Methods: In this prospective study, a total of 121 patients with T2D and estimated glomerular filtration rate (eGFR) ≥ 60 mL/min/1.

Combined effects of sex hormone-binding globulin and sex hormones on risk of incident type 2 diabetes.

Background: The aim of the present study was to investigate the combined effects of sex hormone-binding globulin (SHBG) and sex hormones on the risk of type 2 diabetes (T2D).

Methods: A nested case-control study of Chinese participants in the Environment, Inflammation and Metabolic Diseases Study (2008-13) was performed. Of the 3510 subjects free of diabetes, 145 men and 87 women developed diabetes over the 5-year follow-up.

AMP-kinase pathway is involved in tumor necrosis factor alpha-induced lipid accumulation in human hepatoma cells.

Aim: It is well known that lipid accumulation and inflammation are two important steps in pathogenesis and progress of nonalcoholic fatty liver disease (NAFLD). However, fewer studies have explored the direct relationship between lipid accumulation and inflammation in early NAFLD. Tumor necrosis factor alpha (TNF-α) is one of the classical inflammatory cytokines.