Publications by authors named "Rich Milton R Dulay"
Article Synopsis
- Cancer is the second leading cause of death globally, prompting research into effective natural treatments, particularly from mushrooms which contain cytotoxic compounds.
- Ethanolic extracts from Oudemansiella canarii and Ganoderma lucidum were tested against nine types of hematologic cancer cells, showing significant cell proliferation inhibition and apoptosis activation.
- The study found that these mushroom extracts triggered apoptosis through increased levels of specific apoptotic markers and activated the SAPK/JNK signaling pathway, demonstrating their potential as alternative treatments for hematologic malignancies.
The proximate composition and functionality of Lentinus tigrinus were evaluated to establish and popularize this mushroom as functional food source. The evaluation of functionality focused on the antibacterial and hypoglycemic activities of the mushroom extracts. An acute single oral dose toxicity test in mice was used for its biosafety analysis.
View Article and Find Full Text PDFThis paper highlights the teratogenic and toxic effects of Ganoderma lucidum (Lingzhi or Reishi mushroom) extract on zebrafish embryos. Hatchability, malformations, and lethality rate of zebrafish embryos were assessed to provide valuable information regarding the potential teratogenic activity of G. lucidum.
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