The Small RNA ErsA Impacts the Anaerobic Metabolism of Through Post-Transcriptional Modulation of the Master Regulator Anr.

is one of the most critical opportunistic pathogens in humans, able to cause both lethal acute and chronic lung infections. In previous work, we indicated that the small RNA ErsA plays a role in the regulatory network of pathogenicity in airways infection. To give further insight into the lifestyle functions that could be either directly or indirectly regulated by ErsA during infection, we reanalyzed the categories of genes whose transcription appeared dysregulated in an knock-out mutant of the PAO1 reference strain.