Selective Laser Trabeculoplasty as a Substitute for Medications in Patients with Mild-to-moderate Glaucoma in the Brazilian Public Health System.

Prcis: Selective laser trabeculoplasty can be used as a substitute for medications in patients with mild-to-moderate glaucoma, reducing the cost of eye drop distribution in the Brazilian public health system.

Purpose: To observe the effectiveness of selective laser trabeculoplasty (SLT) as a substitute for eye drops in patients with open angle glaucoma in the Brazilian Public Health System.

Materials And Methods: SLT was performed bilaterally after medication washout.

Standalone Implantation of 2-3 Trabecular Micro-Bypass Stents (iStent inject ± iStent) as an Alternative to Trabeculectomy for Moderate-to-Severe Glaucoma.

Introduction: This retrospective consecutive study compared standalone implantation of multiple (2-3) trabecular micro-bypass stents (iStent inject ± iStent) (Multi-Stent group) vs trabeculectomy + mitomycin C (Trab group) in moderate to severe open-angle glaucoma (OAG).

Methods: Eligible patients underwent Multi-Stent or Trab surgery from 2018 to 2020 and had at least 3-month follow-up; visual field mean deviation (VF MD) - 6 dB or worse; inadequate prior response to maximum medications ± laser procedures; and had trabeculectomy as their next planned intervention. Primary effectiveness, safety-adjusted treatment success, was defined as ≥ 20% intraocular pressure (IOP) reduction on the same or fewer medications, without clinically significant safety events (severe complications, secondary surgeries, reinterventions).

Two-Year Comparative Outcomes of First- and Second-Generation Trabecular Micro-Bypass Stents with Cataract Surgery.

Introduction: This retrospective comparative study assessed real-world effectiveness and safety of first-generation (iStent) and second-generation (iStent inject) trabecular micro-bypass stents with cataract surgery in patients with open-angle glaucoma (OAG).

Material And Methods: Through a 24-month postoperative follow-up, the effectiveness was quantified by intraocular pressure (IOP) reduction; mean glaucoma medication reduction; proportional analysis of eyes meeting IOP cutoffs (<18, <15, <12 mmHg) either with or without medications; and proportional analysis of medication burden. Safety measures included visual acuity, adverse events, and secondary surgery.

Factors Associated With Unqualified Success After Trabecular Bypass Surgery: A Case-control Study.

Precis: An older age, a low number of baseline glaucoma medications, an early glaucoma stage, lower intraocular pressure (IOP) values during the first postoperative month, and combined surgery are possible predictors of unqualified success after a trabecular by-pass microinvasive glaucoma surgery (MIGS) procedure.

Purpose: The purpose of this study was to identify the potential predictors of unqualified success (IOP<18 mm Hg with no glaucoma medication) after trabecular by-pass MIGS.

Materials And Methods: We designed a case-control study using logistic regression modeling that included all trabecular by-pass surgeries with at least 3 months of follow-up, performed at a single center from June 2017 to December 2019.

iStent Inject (Second-generation Trabecular Microbypass) Versus Nonpenetrating Deep Sclerectomy in Association With Phacoemulsification for the Surgical Treatment of Open-angle Glaucoma and Cataracts: 1-Year Results.

Precis: Both nonpenetrating deep sclerectomy (NPDS) and iStent inject are safe and effective when combined with phacoemulsification. The NPDS group presented lower final intraocular pressure (IOP); however, more postoperative intervention and longer recovery time was required.

Aim: The aim of this study was to assess the 1-year efficacy and safety of second-generation trabecular microbypass stent implantation (iStent inject) versus NPDS in association with phacoemulsification (Phaco) for the concomitant surgical treatment of open-angle glaucoma and cataracts.

Use of a Collagen Matrix Implant as an Adjuvant in Combined Surgery Involving Phacoemulsification and Nonpenetrating Deep Sclerectomy.

Aim: To assess the efficacy and safety of the Ologen collagen matrix as an adjuvant for combined phacoemulsification and nonpenetrating deep sclerectomy (Phaco-NPDS), in addition to mitomycin C (MMC).

Materials And Methods: This was a longitudinal retrospective comparative study of eyes treated with Phaco-NPDS, with (group 1) or without (group 2) an Ologen collagen matrix implant, in addition to MMC. The main outcome measures were operative success [absolute success: intraocular pressure (IOP) <18 mm Hg and an at least 20% reduction from baseline without medication; relative success: IOP<18 mm Hg and at least 20% reduction from baseline IOP with or without medication], mean reductions (%) in IOP and medication use; number of postoperative reinterventions (goniopuncture, needling, reoperation), and number of complications.

Does the type of treatment have an influence on utility values in a glaucoma population?

Purpose: To assess the impact of glaucoma therapy on utility values in a glaucoma population.

Methods: A cross-sectional study of consecutive glaucoma patients was conducted. Utility values were obtained using the time trade-off method.

Utility values for glaucoma in Brazil and their correlation with visual function.

Purpose: We sought to identify the utility values in a group of Brazilian patients with primary open-angle glaucoma (POAG), and to assess its impact on visual acuity (VA) and mean deviation index values.

Materials And Methods: This was a cross-sectional study of consecutive patients with POAG, who were interviewed using three methods for obtaining utility values: time trade-off (TTO), standard gamble anchored at risk of death (SG1), and standard gamble anchored at risk of blindness (SG2). Visual function variables (VA and mean deviation index in the better eye) and sociodemographic characteristics (age, sex, race, and educational level) were also obtained for statistical analysis.