Electrophysiological Characterization of Cerebellar Responses during Exploration and Grooming Behaviors in a Rat Model of Parkinsonism.

Parkinson's disease is currently a global public health challenge due to the rapid growth of aging populations. To understand its pathophysiology is necessary to study the functional correlation between the basal ganglia (BG) and the cerebellum, which are involved in motor control. Herein, we explored multiunit electrical activity (MUA) in the cerebellum of rats with induced Parkinsonism as a result of lesions following bilateral placement of electrodes and passing of current in the ventrolateral striatum (VLS).

Sexual behavior and locomotion induced by sexual cues in male rats following lesion of Lobules VIa and VII of the cerebellar vermis.

The cerebellum is an important contributor to the neural basis of sexual behavior, but the specific cerebellar regions underlying different aspects of reproduction are still unknown. Here, we used experimental lesions of Lobules VIa and VII of the vermis to investigate their specific role, both in locomotion stimulated by sexual cues and the execution of sexual behavior. Sexually experienced male rats and receptive females were used, and experimental males received an electrolytic lesion of either lobule.