Publications by authors named "Ricardo Mesquita"

Article Synopsis
  • - The study aimed to compare the fractal dimension (FD) and lacunarity of mandibular bone in patients with osteoradionecrosis (ORN) versus those without, using digital panoramic radiographs and ImageJ software for analysis.
  • - A total of 25 patients were divided into two groups (14 with ORN and 11 without), and while FD and lacunarity values were similar across groups, certain thresholds were identified that helped differentiate between the two populations.
  • - Although the differences in FD and lacunarity were not statistically significant, the effect sizes suggest potential clinical relevance, indicating that these measurements could be useful in evaluating bone health post-radiotherapy.
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There is an interaction between dendrocytes and mast cells in the skin. However, in elastosis-related diseases such as actinic cheilitis (AC) and lower lip squamous cell carcinoma (LLSCC), this interaction remains unknown. We investigated the presence of intact and degranulated mast cells in AC and LLSCC.

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This study aimed to evaluate the pulp response to F18 and cobalt-doped F18 bioglass (F18Co) in comparison with calcium hydroxide (CH) after pulp capping. The maxillary first molars of 48 rats were divided into F18, F18Co, CH, and control (no intervention) groups. The pulp was exposed, the materials were placed, and the teeth were capped.

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Introduction: Leukemia and lymphoma mimicking periapical conditions can lead to significant diagnostic pitfalls. Guidance for endodontists in managing such cases is barely explored. This systematic review aimed to summarize the clinicopathologic, imaging, and management aspects of leukemia/lymphoma that mimicked periapical conditions and resulted in endodontic treatment.

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Background: Treatment for head and neck squamous cell carcinoma (HNSCC) is often associated with various adverse effects, including changes in salivary parameters and complaints of halitosis. This study aimed to investigate changes in volatile sulfur compound (VSC) levels and salivary parameters in patients undergoing treatment for HNSCC.

Methods: This prospective longitudinal study was conducted at a Brazilian oncology center, where a convenience sample of 24 HNSCC patients undergoing radiotherapy or chemoradiotherapy were evaluated for VSC levels, salivary flow, pH, viscosity, dry mouth, and tongue coating.

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The life course approach scrutinizes factors that shape the development of diseases over time. Tooth loss, which is influenced by social, behavioral and biological factors, can occur at various stages of life and tends to become more prevalent in later years. This systematic review examined the influence of socioeconomic, psychosocial, biological and behavioral adversities in life on the likelihood of tooth loss.

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This cross-sectional study aimed to evaluate the interplay between volatile sulfur compounds (VSC), biofilm, salivary parameters, and periodontal status in patients with and without periodontal disease. Sixty-four subjects diagnosed with periodontitis and 60 periodontally healthy individuals were included. Probing depth, clinical attachment level, bleeding on probing, tongue coating index, plaque index, number of teeth, spinnability of unstimulated whole saliva, and salivary flow rate were evaluated.

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The manner in which motoneurons respond to excitatory and inhibitory inputs depends strongly on how their intrinsic properties are influenced by the neuromodulators serotonin and noradrenaline. These neuromodulators enhance the activation of voltage-gated channels that generate persistent (long-lasting) inward sodium and calcium currents (PICs) into the motoneurons. PICs are crucial for initiating, accelerating, and maintaining motoneuron firing.

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Aims: Cerebral palsy (CP) is the term for a set of neurological disorders resulting from brain damage that impairs motor function. The aim of the present study was to perform a systematic review of the literature to determine whether individuals with CP are at a greater risk of negative periodontal health outcomes compared to those without CP.

Methods: This study followed the recommendations of the MOOSE guidelines.

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The response of spinal motoneurons to synaptic input greatly depends on the activation of persistent inward currents (PICs), the contribution of which can be estimated through the paired motor unit technique. Yet, the intra-session test-retest reliability of this measurement remains to be fully established. Twenty males performed isometric triangular dorsiflexion contractions to 20 and 50 % of maximal torque at baseline and after a 15-min resting period.

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Article Synopsis
  • The study investigates Muscle Dysmorphia (MD) and its psychological effects, particularly in sexual minority women like lesbians and bisexuals, which have not been extensively researched.
  • A sample of 479 Brazilian cisgender women (ages 18-70) was analyzed, revealing that 68.27% identified as heterosexual, 27.98% as bisexual, and 3.76% as lesbian.
  • Results showed significant differences, with lesbian and bisexual women experiencing more severe MD symptoms and psychological distress, highlighting the need for more studies focusing on these minority groups.
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  • - The study examines oral lesions in systemic lupus erythematosus (SLE) patients from Latin America, highlighting their varied characteristics and challenges in diagnosis, especially when lesions appear alone.
  • - In a sample of 70 SLE patients, the majority were white females with an average age of 38.4 years, and the most common oral lesions were ulcers, erosions, and white lesions, often found in the hard/soft palate.
  • - Findings suggest that unusual oral changes may signal underlying systemic issues, emphasizing the need for a multidisciplinary approach and regular oral exams to identify and treat these lesions effectively.
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Objective: This systematic review and meta-analysis aimed to compare the occurrence of dental caries and developmental defects of enamel (DDE) in individuals with and without cerebral palsy (CP).

Materials And Methods: We conducted searches across five databases and the grey literature. Data were organized using EndNote 20.

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  • The study examined the presence of Epstein-Barr virus type 1 (EBV-1) DNA in HIV patients with oral hairy leukoplakia (OHL) before and after various topical treatments.
  • A total of 15 patients received different topical therapies, including podophyllin resin alone or in combination with acyclovir or penciclovir, with samples tested for EBV-1 DNA.
  • Results showed clinical healing in all groups, but 73.3% still had EBV-1 detectable after treatment, and some patients experienced recurrences, highlighting a link between treatment type and virus persistence.
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Treatment of oral vascular anomalies (OVA) has focused on minimally invasive techniques rather than radical surgery. We investigated the efficacy and safety of diode laser using the photocoagulation technique in the management of OVA. Forty-seven subjects with OVA were treated with forced dehydration with induced photocoagulation (FDIP) using diode laser (808 nm/4.

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Purpose: Persistent inward calcium and sodium currents (PICs) are crucial for initiation and maintenance of motoneuron firing, and thus muscular force. However, there is a lack of data describing the effects of fatiguing exercise on PIC activity in humans. We simultaneously applied tendon vibration and neuromuscular electrical stimulation (VibStim) before and after fatiguing exercise.

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Aim: To evaluate the influence of an experimental solution of cobalt-doped F18 bioactive glass (F18Co) on tissue repair following regenerative endodontic procedure (REP) in rat molars.

Methodology: The F18Co solution was prepared at a ratio of 1:5 F18Co powder to distilled water. The right or left upper first molars of 12 Wistar rats were used, where the pulps were exposed, removed, and irrigated with 2.

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The aim of this study was to analyze the expression of mast cell markers toluidine blue, c-kit, and tryptase and presence of mononuclear inflammatory cells in oral lichen planus (OLP) and oral lichenoid lesions related to dental amalgam. Nineteen specimens of OLP, OLLC, and healthy oral mucosa were selected. Mononuclear inflammatory cells were analyzed.

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Article Synopsis
  • - The study analyzed neutrophil extracellular traps (NET) and specific salivary cytokines in patients undergoing chemotherapy to examine their links to oral mucositis (OM) and Candida infections.
  • - Among 60 patients, 43.3% experienced OM and 20% had oral candidiasis, with a significant finding that those with OM had different levels of certain cytokines compared to others.
  • - The results suggest that Candida infections can influence cytokine levels and NET formation in patients with chemotherapy-induced OM, even without visible signs of candidiasis.
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  • - Follicular lymphoma is a type of cancer arising from B cells in the germinal center, often identified through microscopic and molecular analysis, particularly in the oral cavity.
  • - A study evaluated 20 cases of oral follicular lymphoma, noting similar occurrences in men and women, with lesions commonly found in the palate and buccal mucosa, and a majority classified as grades 1 and 2.
  • - Genetic testing revealed various translocations in specific genes, with the overall survival rate at 88% over two years, indicating that while these lymphomas are rare in the mouth, they typically present as non-ulcerated swellings.
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  • The study investigates how anxiety and depression affect oral mucositis in patients undergoing chemotherapy, highlighting a gap in existing research on this topic.
  • A longitudinal study was conducted with 37 participants, assessing their mental health and quality of life before and after chemotherapy using specific questionnaires.
  • Results showed that nearly 38% of patients developed oral mucositis and experienced higher levels of anxiety and depression, significantly impacting their overall health and quality of life related to oral health.
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This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients' histopathological records.

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Background: This study aimed to investigate the clinicopathological features of metastases in the oral and maxillofacial regions.

Methods: In this retrospective study, biopsy records were obtained from referral centers for oral and maxillofacial diagnosis in Brazil, Guatemala, Mexico, and South Africa.

Results: A total of 120 cases were evaluated.

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Photobiomodulation therapy (PBMT) is widely used in oncology settings, but lack of assessment standardization is the main barrier to optimization of clinical protocols. This study analyzed three PBMT protocols for preventing oral and oropharyngeal mucositis (OM) in patients undergoing chemotherapy (CT) and/or hematopoietic stem cell transplantation (HSCT). This is a preliminary randomized blind clinical trial.

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