Publications by authors named "Ricardo Mamber Czeresnia"
Article Synopsis
- Pregnancy involves a complex immune balance where the mother's immune system accepts a genetically distinct fetus while still defending against infections, largely mediated by signals from trophoblast cells.
- Villitis of unknown etiology (VUE) disrupts this immune tolerance, allowing maternal immune cells to invade and damage fetal tissue, which can lead to complications during pregnancy and potential recurrence in future pregnancies.
- Research indicates that VUE placentas show lower levels of important immune checkpoint proteins like PD-L1 and higher counts of activated immune cells (PD-1 and LAG3) compared to normal and cytomegalovirus-infected placentas, suggesting that immune checkpoint dysfunction may contribute to the disease's progression.
SARS-CoV-2 and Pregnancy: A Review of the Facts.
Rev Bras Ginecol Obstet
September 2020
Objective: The present comprehensive review aims to show the full extent of what is known to date and provide a more thorough view on the effects of SARS-CoV2 in pregnancy.
Methods: Between March 29 and May, 2020, the words , , , , and were searched in the PubMed and Google Scholar databases; the guidelines from well-known societies and institutions (Royal College of Obstetricians and Gynaecologists [RCOG], American College of Obstetricians and Gynecologists [ACOG], International Society of Ultrasound in Obstetrics & Gynecology [ISUOG], Centers for Disease Control and Prevention [CDC], International Federation of Gynecology and Obstetrics [FIGO]) were also included.
Conclusion: The COVID-19 outbreak resulted in a pandemic with > 3.