Publications by authors named "Ricardo Magana"
Combined endoscopic transorbital and transnasal approach for the management of a solitary plasmacytoma of the sphenoid bone: A case report and literature review.
Omar R Ortega-Ruiz Jorge Armando Lara Olivas Marcos V Sangrador-Deitos Ricardo Marian Magaña Jose Augusto Ruiz Gurria
Surg Neurol Int
February 2024
Background: Parasellar plasmacytomas are rare neurosurgical entities. Intrinsic characteristics of these tumors, such as adjacent bone erosion and symptoms resulting from invasion and mass effect, may lead to the possibility of a solitary extramedullary plasmacytoma (SEP) as a differential diagnosis.
Case Description: We present the case of a 39-year-old male with a 1-month history of bilateral decreased visual acuity, retroocular pulsating pain, and chromatic vision loss.
Article Synopsis
- Amphotericin B is a powerful antifungal, but its use is limited due to high toxicity, prompting research for safer derivatives.
- The study focused on the molecular mechanism of polyene action, examining various scientific aspects to develop a new, safer version called L-histidine methyl ester of Amphotericin B.
- This new derivative exhibits similar antifungal action as the original but shows reduced dimerization, leading to greater selectivity and improved safety in preclinical tests.