Assessment of glomerular filtration rate in the neonate: is creatinine the best tool?

Purpose Of Review: This article answers the question of whether creatinine is the best biomarker for monitoring neonatal glomerular filtration rate (GFR) in view of recent advances in measuring neonatal renal function.

Recent Findings: We rely largely on serum creatinine for the estimation of GFR in the newborn, even though creatinine is freely exchanged through the placenta. During the first few days of life, the serum creatinine reflects maternal renal function or the maternal creatinine.

[Nutcracker syndrome: Cause of non-glomerular hematuria and massive proteinuria].

Background: Nutcracker syndrome caused by compression of the left renal vein between the aorta and superior mesenteric artery is a non-glomerular cause of left renal bleeding and left varicocele. It has also been recognized to be an important cause of orthostatic proteinuria.

Case Report: A 17-year-old male was evaluated due to recurrent macroscopic hematuria.