Mutation rates in 21 autosomal short tandem repeat loci in a population from Goiás, Brazil.

The appearance of new mutations in polymorphic markers plays a central role in a range of genetic applications, including dating phylogenetic events, informing disease studies, and evaluating forensic evidence. The present study estimated the mutation rates of 21 autosomal STR loci in a population from Central Brazil. We studied 15 046 paternity cases from Goiás, Brazil from August 2012 to February 2015.

The effect of low-dose exposure on germline microsatellite mutation rates in humans accidentally exposed to caesium-137 in Goiânia.

A serious radiological accident occurred in 1987 in Goiânia, Brazil, which lead to extensive human and environmental contamination as a result of ionising radiation (IR) from caesium-137. Among the exposed were those in direct contact with caesium-137, their relatives, neighbours, liquidators and health personnel involved in the handling of the radioactive material and the clean-up of the radioactive sites. The exposed group consisted of 10 two-generation families, totalling 34 people.

Allele frequencies of fifteen STR loci in a population from Central Brazil.

Allele frequencies for 15 short tandem repeats included in Powerplex 16 Kit (Penta E, D18S51, D21S11, TH01, D3S1358, FGA, TPOX, D8S1179, vWA, Penta D, CSF1PO, D16S539, D7S820, D13S317 and D5S818) were determined in a sample of 429 unrelated individuals from the population of Goiânia, Goias, Central Brazil. Determination of the allele frequencies as well as of several commonly used statistics in forensic and paternity testing were defined. The forensic parameters presented high values and the most polymorphic loci were Penta E, following FGA and D18S51.