Publications by authors named "Ricardo Cuesta Martin de la Camara"
Background: Epstein-Barr virus (EBV) specific T-cell response measurement can help adjust immunosuppression in transplant patients with persistent infections. We aim to define T-cell responses against EBV in a cohort of pediatric liver-transplant patients.
Methods: Thirty-eight immunosuppressed pediatric liver-transplant patients (IP) and 25 EBV-seropositive healthy-adult controls (HC) were included in our cross-sectional study.
Background: Genetic diagnosis of inborn errors of immunity (IEI) is complex due to the large number of genes involved and their molecular features. Missense variants have been reported as the most common cause of IEI. However, the frequency of copy number variants (CNVs) may be underestimated since their detection requires specific quantitative techniques.
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- Inborn errors of immunity (IEI) are conditions that weaken the immune system, making it challenging to evaluate infection risk and vaccine responses, particularly after SARS-CoV-2 vaccination.
- This study focused on analyzing the immune responses of IEI patients by measuring specific memory B cells and antibodies both before and after vaccination.
- Results showed varying immune responses in IEI patients, with some exhibiting adequate responses, while others demonstrated significant deficiencies, highlighting the unpredictable nature of humoral and T-cell responses in this group.