Integration of 3D Fluorescence Imaging and Luminescent Thermometry with Core-Shell Engineered NaYF:Nd/Yb/Ho Nanoparticles.

The design of rare-earth-doped upconversion/downshifting nanoparticles (NPs) for theoretical use in nanomedicine has garnered considerable interest. Previous research has emphasized luminescent nanothermometry and photothermal therapy, while three-dimensional (3D) near-infrared (NIR) luminescent tracers have received less attention. Our study introduces Nd-, Yb-, and Ho-doped NaYF core-shell luminescent NPs as potential multiparametric nanothermometers and NIR imaging tracers.

Influence of symmetry on the magneto-optical properties of a bifunctional macrocyclic Dy complex.

In this work, a novel complex, [Dy(L)(NO)]·(HO)·(NO) (1), containing a highly distorted macrocyclic ligand (L) and weak axial anions (NO), was synthesized and characterized. Even though this coordination environment is not ideal for maximizing the magnetic anisotropy of a Dy ion, a magneto-structural analysis reveals that the high distortion of the macrocycle promotes a disposition of the hard plane and easy axis opposite to the expected one. This results in a quite symmetrical environment which allows obtaining a field induced SMM behaviour.

Effect of fermentation on the physicochemical characteristics and sensory quality of Arabica coffee.

This work aims to assess the physicochemical characteristics and final sensory quality of Yellow Catuai IAC 62 Arabica coffee fermented with . For such a purpose, a Composite Central Rotational Design (CCRD) was performed to investigate how fermentation time,temperature and pH conditions, moisture content and concentration of sugars and organic acids affect its sensory quality on two different roast levels in accordance with Specialty Coffee Association (SCA) protocols. It was found that fructose concentration decreased from 12 g/L to around 5 g/L during fermentation, regardless of temperature condition.

Immunogenic Cell Death Photothermally Mediated by Erythrocyte Membrane-Coated Magnetofluorescent Nanocarriers Improves Survival in Sarcoma Model.

Inducing immunogenic cell death (ICD) during cancer therapy is a major challenge that might significantly improve patient survival. The purpose of this study was to develop a theranostic nanocarrier, capable both of conveying a cytotoxic thermal dose when mediating photothermal therapy (PTT) after its intravenous delivery, and of consequently inducing ICD, improving survival. The nanocarrier consists of red blood cell membranes (RBCm) embedding the near-infrared dye IR-780 (IR) and camouflaging Mn-ferrite nanoparticles (RBCm-IR-Mn).

Photothermal Properties of IR-780-Based Nanoparticles Depend on Nanocarrier Design: A Comparative Study on Synthetic Liposomes and Cell Membrane and Hybrid Biomimetic Vesicles.

Biomimetic nanoparticles hold great promise for photonic-mediated nanomedicine due to the association of the biological functionality of the membrane with the physical/chemical goals of organic/inorganic structures, but studies involving fluorescent biomimetic vesicles are still scarce. The purpose of this article is to determine how photothermal therapy (PTT) with theranostic IR-780-based nanoparticles depends on the dye content, cholesterol content, lipid bilayer phase and cell membrane type. The photophysical responses of synthetic liposomes, cell membrane vesicles and hybrid nanoparticles are compared.

Dual visible and near-infrared luminescence in mononuclear macrocyclic erbium(III) complexes ligand and metal centred excitation.

Considering the structural design of some of the scarce molecular-based Er-centred emitters in the literature, we explored the optical properties of three Er hexaazamacrocyclic complexes, namely Er-EDA (1), Er-OPDA(2) and Er-DAP(3). The macrocyclic ligands in these complexes differ in the lateral spacers, and are derived from 2,6-pyridine-dicarbaldehyde and ethylenediamine (EDA), -phenylenediamine (OPDA) or 1,3-diaminopropane (DAP). Upon ligand-centred excitation, the bluish-green and green emissions of the Er ion were detected only for the complexes containing macrocycles with aliphatic spacers (1 and 3), which evidenced that these ligands can sensitize the Er luminescence.

Evaluation of antiplasmodial activity and cytotoxicity assays of amino acids functionalized magnetite nanoparticles: Hyperthermia and flow cytometry applications.

We report the synthesis of magnetite nanoparticles (MNP) and their functionalization with glycine (MNPGly), β-alanine (MNPAla), L-phenylalanine (MNPPhAla), D-(-)-α-phenylglycine (MNPPhGly) amino acids. The functionalized nanoparticles were characterized by Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD), electron paramagnetic resonance (EPR), vibrating sample magnetometry (VSM), Mössbauer spectroscopy (MS), magnetic hyperthermia (MH), dynamic light scattering and zeta potential. The functionalized nanoparticles had isoelectric points (IEP) at pH ≃ 4.

Immobilization of β-galactosidase from Bacillus licheniformis for application in the dairy industry.

The food industry has developed a wide range of products with reduced lactose to allow people with intolerance to consume dairy products. Although β-galactosidase has extensive applications in the food, pharma, and biotechnology industries, the enzymes are high-cost catalysts, and their use makes the process costly. Immobilization is a viable strategy for enzyme retention inside a reactor, allowing its reuse and application in continuous processes.

Enhancement of Terbium(III)-Centered Luminescence by Tuning the Triplet Energy Level of Substituted Pyridylamino-4-R-Phenoxo Tripodal Ligands.

A series of luminescent phenoxo-bridged dinuclear Tb complexes with tripodal ligands, 2,2'-[[(2-pyridinylmethyl)imino]di(methylene)]-bis(4-R-phenol), where R = CH (L) (), Cl (L) (), CHO (L) (), COOCH (L) (), were prepared to probe the effect of -substitution on the phenol ring of the ligand on the Tb luminescence. For these Tb complexes a complete suppression of the ligand-centered fluorescence is observed, which demonstrates an efficient ligand-to-metal energy transfer. Complex was found to be the one that shows the greater intensity of the emission at room temperature.

Tuning White Light Emission in Dinuclear Phenoxo Bridged Dy Complexes.

A new series of dinuclear dysprosium(III) complexes, [Dy(L)(NO)(MeOH)] (), [Dy(L)(NO)(DMF)]·2DMF (), [Dy(L)(NO)(DMF)]·2DMF (), and [Dy(L)(NO)(DMF)] (), with 2,2'-[[(2-pyridinylmethyl)imino]di(methylene)]bis(4-R-phenol), where R = CH, Cl, and CHO, were investigated as potential white light emitters. All octacoordinated dysprosium(III) are phenoxo-bridged species and have a similar coordination environment. Nevertheless, has a MeOH ligand molecule, while for - a DMF ligand replaces that of MeOH.

A Blue-Light-Emitting Cadmium Coordination Polymer with 75.4% Photoluminescence Quantum Yield.

We report a novel bright deep-blue-emitting crystal form based on a simple cadmium coordination polymer with an impressive external photoluminescence quantum yield of 75.4(9)%.

1D magnetic interactions in Cu(II) oxovanadium phosphates (VPO), magnetic susceptibility, DFT, and single-crystal EPR.

We report the crystal face indexing and molecular spatial orientation, magnetic properties, electron paramagnetic resonance (EPR) spectra, and density functional theory (DFT) calculations of two previously reported oxovanadium phosphates functionalized with Cu(II) complexes, namely, [Cu(bipy)(VO2)(PO4)]n (1) and [{Cu(phen)}2(VO2(H2O)2)(H2PO4)2 (PO4)]n (2), where bipy = 2,2'-bipyridine and phen = 1,10-phenanthroline, obtained by a new synthetic route allowing the growth of single crystals appropriate for the EPR measurements. Compounds 1 and 2 crystallize in the triclinic group P1̅ and in the orthorhombic Pccn group, respectively, containing dinuclear copper units connected by two -O-P-O- bridges in 1 and by a single -O-P-O- bridge in 2, further connected through -O-P-O-V-O- bridges. We emphasize in our work the structural aspects related to the chemical paths that determine the magnetic properties.